Writer:	David Zabel, Joe Sachs
Director:	John Wells
Star:	Maura Tierney (Dr. Abby Lockhart),  Goran Visnjic (Dr. Luka Kovac),  John Stamos (Dr. Tony Gates),  Scott Grimes (Dr. Archie Morris),  Linda Cardellini (Nurse Sam Taggart),  Parminder Nagra (Dr. Neela Rasgotra),  Mekhi Phifer (Dr. Greg Pratt)
Recurring Role:	Steven C. Parker (Harold Zelinski (as Steven Christopher Parker)),  Aidan/Andrew Gonzales (Joe Kovac (uncredited)),  Lily Mariye (Lily),  Yvette Freeman (Haleh),  Troy Evans (Frank),  Laura Cerón (Chuny),  Leland Orser (Dr. Lucien Dubenko),  Gil McKinney (Dr. Paul Grady),  Montae Russell (Zadro)
Guest Star:	Tony Sancho (Emilio),  Zoran Radanovich (Niko),  Lewis T. Powell (Workman),  Ingrid Oliu (Conchita (as Ingrid Oliu-Ostrum)),  James Mathers (Security Guard),  Pramod Kumar (Bheru),  Elizabeth Graham (Melissa Tanner),  Kiplan Dooley (Van),  Dee Dee Davis (Evie),  Tom Astor (Leahy),  Reiko Aylesworth (Julia Dupree),  Nicholas Weiland (Lowell Tanner),  DeSean Terry (Rodney),  Arnell Powell (Del),  April D. Parker (Joyce),  Peter Fonda (Pierce Tanner)

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Morris: If we keep this thing cranking, we could hit 300. That's quite a milestone. (play on words that could be taken as the milestone of the 300th episode, or the milestone of reaching 300 patients) (edit) Pierce: My name is Pierce.
Lowell: My name is Lowell.
Pierce: Oh... (shaking hands with Lowell) Lowell, I'm your father.
Lowell: (almost crying) Nice to meet you. (edit) Julia: (as names of deceased patients roll on a screen) The names of those who passed on while under our care. We take time from our busy day to pay respect to the mothers and fathers, husbands and wives, sisters and brothers, sons and daughters who are no longer with us. Think of one patient who's changed you in some way. Hold them in your memory. (Gates thinks of Joshua Lipnicki) Were they inspiring? Funny? (Morris thinks of Willis Peyton) Corageous? Did they challenge you? (Neela thinks of Teller) Teach you something about yourself? (Pratt thinks of Charlie Metcalf) Were they searching for something? (Luka thinks of Curtis Ames) Was their heart filled with love? (Abby thinks of Dr. Nate Lennox) As you hold them in your mind ask yourself: which of their qualities can be part of my life? (edit) Abby: I started drinking again.
Luka: When?
Abby: The night Joe got hurt. And I (long pause) can't stop.
Luka: I thought when I came back, we just had to get used to being married again. But then things didn’t get better and I thought... (long pause) So what do we do?
Abby: I need to fix it. I need to go somewhere, a facility, with professionals, and get better. And I need to believe it this time, and I need you to believe it. (long pause) And I need you to help me. (another long pause) So... so, take Joe... go to Croatia, for your father, while I do that.
Luka: (incredulous)You want us to go without you?
Abby: Yeah, I just...
Luka: But you’re his mother!
Abby: I know that! I know that! (pause) But I haven’t been a very good one. And I honestly don’t think I can be until I deal with this.
Luka: Can’t we do this together?
Abby: This is how we do it together! You have to help me do it... alone.
(long pause)
Luka: That’s it? (pause) Is there anything else...
Abby: (looks at him for a long moment) What do you mean?
Luka: ...that you want to tell me?
Abby: (turns away) I know... I just... I was out of control, I got... out of control... and I... I did some things.
Luka: What kind of things?
Abby: Things I’m ashamed of.
Luka: Okay, just tell me everything.
Abby: (slowly shaking her head) Luka...
Luka: After all this, after everything you don’t want to tell me?
Abby: Not tonight.
(long, long pause; Luka sits next to her, breathes out audibly with pain in his voice, his face in his hands; he looks up, and there is another long, long pause)
Luka: It’s my fault, isn’t it?
Abby: No, don't. (both of them begin to cry) Please don’t...
Luka: I should have come home earlier, I shouldn’t have left you...
Abby: No! I should have been able to handle this!
Luka: I broke my promise!
Abby: Don’t do that, okay?! Don’t! I screwed up! I screwed up because I couldn't keep it together!
Luka: (at the same time) I’m sorry, I’m so sorry, I’m sorry, I’m so...
Abby: This is my fault! It's my fault, it’s me! And please, don’t, don't. Just don’t... (Abby places her hand on his back, and pauses for a long, long moment) I’m sorry.
(they sit quietly together, in so much pain) (edit) Sam: I don't care what anybody says Gates, I think you're a half decent guy. (edit)

The 300th patient is Frank (thanks to Morris). (edit)

Episode's Title: "300 Patients"

The episode's title is actually a reference to the number of this episode according to the show's lifetime; in this case, 300. (edit)