Writer:	Mark Wilding
Director:	Tom Verica
Star:	Chandra Wilson (Miranda Bailey),  Ellen Pompeo (Meredith Grey),  Eric Dane (Mark Sloan),  Isaiah Washington (Preston Burke),  James Pickens Jr. (Richard Webber),  Justin Chambers (Alex Karev),  Kate Walsh (Addison Montgomery Shepherd),  Katherine Heigl (Isobel "Izzie" Stevens),  Patrick Dempsey (Derek Shepherd),  Sandra Oh (Cristina Yang),  Sara Ramirez (Calliope "Callie" Torres),  T.R. Knight (George O'Malley)
Recurring Role:	Elizabeth Reaser (Jane Doe),  Kali Rocha (Sydney Heron)
Guest Star:	Mitch Pileggi (Larry Jennings),  Mary-Margaret Humes (Nancy Jennings),  Rowena King (Celeste Newman),  Ramon De Ocampo (James Benton),  Stewart Skelton (Dr. Fischer)

International Air Dates:
The Netherlands: May 28, 2007 on Net 5
Italy: June 25, 2007 on Foxlife
New Zealand: June 28th, 2007 on TV2
Latin America: July 2nd, 2007 on Sony Entertainment Television
Australia: July 22nd, 2007 on Channel 7
Israel: July 30, 2007 on Yes Stars 1
Ireland: October 16, 2007 on RTE Two
Germany: November 7, 2007 on Pro7
Sweden: November 7, 2007 on Kanal 5
Norway: January 8, 2008 on TV 2
Finland: January 23, 2008 on Nelonen
Croatia: February 11, 2008 on NOVA TV
Czech Republic: April 6, 2008 on Prima (edit) Music featured in this episode:
"Nausea" by Beck
"Better Off" by Let's Go Sailing
"Again & Again" by The Bird and the Bee
"The Secrets of Amanda Prines" by The Reddmen
"Breath" by Breaking Benjamin
"How Am I Doing?" by Anna Waronker (edit)

Meredith (voiceover): As interns, we know what we want, to become surgeons. And we'll do anything to get there. Suffer through killer exam, endure one-hundred hour weeks, Stand for hours on end in operating rooms, you name it, we'll do it. (edit) Izzie: I don’t know how we do this. I don’t know how we work together and be friends and act like it’s all okay.
George: I... there’s a spot available at Mercy West. I called them.
Izzie (shocked): You’re gonna transfer to Mercy West?
George: I have to. (edit) Derek: What're you doing here?
Meredith: I wanted you to know where I was, so I thought I'd come and tell you.
Derek: Ah, you're mocking me.
Meredith (kisses his neck): I'm apologizing.
Derek: You're making light of things.
Meredith: I'm running my fingers through your hair. I'm standing in your bedroom, unbuttoning my shirt. And I'm taking off my pants. And now, I'm getting into your bed, naked. (edit) Izzie: I need a vault. (to Burke) Can you be a vault? Because I've eaten a cake and a half and it's just not cutting it. And you don't gossip.
Burke: Well, that's because nobody tells me anything.
Izzie: I slept with a married man. It was...
Burke (interrupts): I don't mind that nobody tells me anything.
Izzie: It was George. It was with George.
Burke (eats a piece of cake): It should be firm inside and not spongey. The frosting, marang, light, but not too sweet. I always thought chocolate inside but...I've been leaning nowhere with that.
Izzie: You've thought a lot about this cake.
Burke: This cake or this day? With this woman.
Izzie: The red velvet is your winner by the way. (edit) Ava: You and Red make a pretty good team.
Alex: Don't tell Sloan.
Ava: Oh, she and Sloan aren't happenin'. She wants you.
Alex: How do you know that?
Ava: I know everything, remember? I heard her talking to the ortho doc about how she wants someone who barbecues and plays catch. She wants someone who's committed.
Alex: Yeah, well that's not me.
Ava: I hate to tell you this, but it is. You may talk tough, but you're a decent guy, Alex. Whether you wanna admit or not, you're one of the good ones. (edit)

Mitch Pileggi and James Pickens Jr. work together again after they worked in many season of X-Files, interpreting Assistant Director Walter Skinner and Assistant Director Kersh, respectively. (edit)

The type of catfish featured in this episode is Vandellia cirrhosa, also known as Candirú and it's feared by Amazonian natives because they really do like to swim into body orifices.
(edit) Episode Title: "Desire"

This episode's title refers to songs by Andy Gibb, U2, Talk Talk, Do As Infinity, Geri Haliwell and Savanah. (edit)