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At a family swim party, the father Richard is paralyzed in a wheelchair, and non-responsive to his family. Then he drives the wheelchair into the pool.

House is jogging to work, while Cuddy and Wilson discuss the paralyzed man’s case among others to find one to hit him with on his first day back since his recovery. Cuddy wonders if the ketamine treatment might wear off but House believes it’s permanent. They give him the case of a woman practicing yoga who apparently snapped her neck and went into paralysis but the x-rays show no spinal damage. House is interested, but also notices Richard’s case and ignores the report of brain cancer, deciding to take both cases.

House starts with his staff on diagnosis of the yoga woman and then Richard. House has the man undergo tendon surgery to make him more comfortable while House talks with the wife Arlene and son Mark. Mark believes it was an accident but House suggests it might be suicide, but that means his dad is still there. Cameron interrupts to tell him something about the woman but is more interested in House actually meeting with his patient and his family. House finally discovers that the paralyzed woman, Caren, can move and tells her to get out despite her claims that she’s not faking.

Later Wilson asks House about his meeting with the patient’s family and wonders if House is looking for a normal case to give himself meaning after his shooting and hallucination. House wonders why he didn’t feel anything when the wife thanked him, but he’s called in to check Caren, who is having tightness of the chest. House thinks she’s bluffing again and tries to bluff her out of it and then realizes she has a congested heart and starts draining off the fluid.

They have to continue draining the blood off and go back to differential diagnosis. House suspects the paralysis was delusional but she also had a heart condition and orders exploratory surgery. Cuddy meets with House to question him on the exploratory surgery and tells him to stop, as well as reduce Richard’s morphine drip.

Wilson confronts House on his issues again and after the tests prove negative, the exploratory surgery on Caren is on. House notices that her toenail is discolored and cancels the surgery. It turns out she has scurvy due to a lack of Vitamin C. Richard is being released and House and Arlene talk out her intent to keep caring for her husband and House wonders how it reflects on him. But as she lifts him out of bed House hears him making gurgling noises and realizes he’s talking.

House orders a new differential diagnosis on Richard and Wilson suspects House is bored now that he’s “normal” and trying to come up with a mystery. As he leaves he notices pain in his formerly bad leg.

House’s staff put together all the symptoms and House suspects a pancreatic cyst and orders an ultrasound, but Foreman warns Richard’s throat will collapse. House dismisses his concerns and has Cameron get Arlene’s consent. Chase begins the procedure but Richard’s throat collapses and they’re forced to trach him and remove the probe.

Richard recovers but they determine the pancreas was clean. House suspects first cancer and then notes the throat locked down rather than collapsed, and there’s a lesion disrupting the signals. House wants to go into Richard’s brain and Cameron tells him to go to Arlene himself. He does so and hints it might help him recover, and Arlene approves, saying Richard’s already dead. They run the test but notice bleeding from his ear--he's hemorrhaging from the brain.

The staff confronts House and he goes over the symptoms again. First Cameron and then Foreman refuse, but Chase goes along with it. Cuddy calls House on it and accuses him of playing a hunch, then says she’ll be sending Richard home the next morning. House goes to Wilson and reveals his leg hurts and wants Vicodin, but Wilson thinks it’s middle-age pains and House is either overreacting or trying to scam him. House goes jogging and ends up trying to cool down in a fountain, then figures it out.

House goes to Cuddy’s house via the window and reveals that Richard has hyperthamlic disregulation and tried to cool off by driving himself into the pool--he has Addison’s disease. Cuddy is still skeptical and refuses to okay the cortisol treatment necessary to cure Richard.

The next morning Richard is discharged and House acknowledges to Wilson that Cuddy was right and he has no reason to believe he’s right. But Cuddy is watching Arlene take her husband out and administers a cortisol injection. She tests him for reaction and initially he shows something, but as they get in the elevator Richard reacts, releasing his safety belt and getting up to walk.

Cuddy goes to tell House but Wilson tells her not to do it, because all he did was get lucky. She reluctantly agrees. At the end House sneaks into Wilson’s office and writes himself a prescription for Vicodin.