Writer:	Matt Witten
Director:	Peter O'Fallon
Star:	Jennifer Morrison (Dr. Allison Cameron),  Jesse Spencer (Dr. Robert Chase),  Lisa Edelstein (Dr. Lisa Cuddy),  Omar Epps (Dr. Eric Foreman),  Hugh Laurie (Dr. Gregory House),  Robert Sean Leonard (Dr. James Wilson)
Recurring Role:	Chi McBride (Edward Vogler),  Bobbin Bergstrom (ICU Nurse)
Guest Star:	Joe Morton (Senator Gary H. Wright),  Missy Crider (Susan),  Elizabeth Karr (Hostess),  Dominic Oliver (Reynolds),  Sahar Bibiyan (Clinic Nurse)

This is the first on-screen appearance of Bobbin Bergstrom, who is also the show's on-site medical adviser. (edit) The tune House plays on his piano during the scene that shows he has twelve messages on his phone is "High Hopes." (edit) Music in closing scene where Cameron says goodbye is "It's Okay to Think About Ending" by Earlimart. (edit)

House: I am selling my soul.
Dr. Wilson: Just a little piece. And you are getting something in return.
House: I said I was selling it. I didn't say I was giving it away. That would be immoral and stupid. (edit) House: But, when you’re 4th down, 100 to go, in the snow, you don’t call a running play up the middle. Unless you’re the Jets.
Dr. Cameron: I hate sports metaphors. (edit) Wright: It must be miserable, always assuming the worst in people.
House: Cut the crap, you're dying!
Wright: And you're clever, you're witty and you are a coward. You're scared of taking chances.
House: I take chances all the time. It's one of my worst qualities.
Wright: On people?
House: (he pauses a while considering) Wanting to believe the best about people doesn't make it true.
Wright: Being afraid to believe it doesn't make it false. (edit) Dr. Cameron: I thank you because it means something to me, to be grateful for what I receive.
House: You are the most naive atheist I've ever met. (edit) Dr. Cameron: You don’t need to worry about firing anyone. I’m leaving.
House: Why? Is this another noble, self-sacrificing gesture? You trying to protect Foreman?
Dr. Cameron: No.
House: So this is just, "Don’t fire me, I quit."
Dr. Cameron: I’m protecting myself. You asked me why I like you. You’re abrasive and rude, but I figured everything you do, you do it to help people. But I was wrong. You do it because it’s right. (edit)

Foreman explains to the senator that Toxoplasmosis is caused by a fungus, however this disease is caused by a protozoan called Toxoplasma gondii. (edit) When House tests the senator for HIV, he orders an ELISA test, which confirms an infection by detecting antibodies to the virus. Nowadays, however, it is hospital policy to use tests that detect viral cells as well as antibodies rather than ELISA because they are quicker and more reliable. Secondly, the PCR test usually isn't used as a confirmatory test, but as a rapid test for medical staff. Besides, doctors are legally bound to run the confirmatory test before telling the patient about the infection. (edit)

House: Are you comparing me to God? I mean, it's great, but so you know, I've never made a tree.
This line is in reference to the last couplet of Joyce Kilmer's famous poem, Trees: "Poems are made fools like me, but only God can make a tree." (edit) Dr. Foreman: Oh, come on. Kennedy had Addison’s, FDR had polio.
Foreman is talking about two popular former U.S. Presidents, Franklin Delano Roosevelt, who served twelve years (1933-1945), and John F. Kennedy, who only served three years (1961-1963) before being assassinated. Both were very well-liked and successful presidents, despite their handicaps. (edit) House: Fine, have it your way. Immaculate conception.
The Immaculate Conception refers to the conception of Mary, the mother of Jesus, preserving her from original sin. (edit)