Grey's Anatomy

A Change Is Gonna Come

Season 4, Ep 1, Aired 9/27/07
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  • Episode Description
  • Entering their first year as residents, Meredith Grey, Cristina Yang, Izzie Stevens and Alex Karev now have interns of their own to mentor. The interns are welcomed by new chief resident Callie. Among the new interns are George, forced to repeat his internship after failing his exams, and Lexie Grey, Meredith's half-sister. Many new interns will be introduced in this season premiere. And they'll have their hands full when a three-car accident sends multiple casualties pouring into Seattle Grace. Some of the doctors need to deal with their new stressed out interns. A young boy brings his bleeding deer to the hospital in the hope a doctor will save her. Cristina searches for Burke. Richard resumes his post as chief of surgery. Derek and Meredith reach an impasse. Bailey wrestles with things at the hospital not turning out like she thought they would.moreless

  • Cast & Crew
  • Ellen Pompeo

    Dr. Meredith Grey

  • Sandra Oh

    Dr. Cristina Yang

  • Katherine Heigl

    Dr. Isobel "Izzie" Stevens

  • Justin Chambers

    Dr. Alex Karev

  • T.R. Knight

    Dr. George O'Malley

  • Fan Reviews (59)
  • What was that?

    By lozza1525, Feb 11, 2008

  • A new set of interns arrives at Seattle Grace Hospital.

    By Valentine_76, Mar 14, 2011

  • This season premiere was good, we get to see changes (nwe people, looks, relationships), still is not good enough. Grey's Anatomy is getting further and further from the previous seasons (and that's no good)

    By g_anatomy, Feb 20, 2008

  • Season 4 Premiere where everyone deals with the aftermath of what happened in the season 3 finale.

    By Starghella, Sep 28, 2007

  • Lexie is Cristina's intern, George is Meredith's intern. Alex misses Rebecca and Cristina misses Burke. Callie struggles as Chief Resident whilst Bailey is still dealing with not getting the job. Meredith and Derek are broken up but not broken up...

    By spongebodge, Sep 28, 2007

  • Trivia & Quotes
  • Quotes (30)

    • Meredith: I...uhm.... Derek: You're not ready for this. Meredith: No. Derek: I asked for too much. Meredith: I think so. Derek: So, this is it? Meredith: Yeah. Derek: We're breaking up? Meredith: We're breaking up. Derek (walks to Meredith): We're broken up. Meredith: It's done. (they start kissing) Derek: Break-up kiss. Meredith: Break-up kiss. Derek (removes his jacket): And some break-up sex. Meredith: Yeah, break-up sex.

    • Callie: What? You wanna humiliate me some more? 'Cause I get it. I suck. I suck at my job, I suck as a wife, I suck all around, so... go ahead, humiliate me some more, please. Bailey: Hope tomorrow's better.

    • Alex: I filled this entire bag with coins from my patients stomach today. Cristina: No kiddin'. Alex (long pause): I miss Rebecca. Cristina (long pause): I miss Burke. Alex (holds up the bag of coins): You want some money? (Cristina smiles)

    • Cristina (to her interns): I have five rules. Memorize them. Rule number one, don't bother sucking up. I already hate you, that's not gonna change. Izzie: Traumas protocol, phone lists, pagers. The nurses will page you, you answer every page at a run. A run. That's rule number two. (notices the interns are not following her) You're supposed to follow me. Alex: Your first shift starts now and lasts 36 hours. You're grunts, nobodies, the bottom of the surgical food chain. You run labs, write orders, work every second night until you drop. And you don't complain. Meredith: On call rooms. Sleep when you can, where you can. You know, but not with anybody. Not attendings, especially not attendings. Sleeping with attendings, not a good idea. Where was I? George: Er, rule number three. If you're sleeping, do not wake you unless the patient is actually dying. Cristina: The dying patient better not be dead when I get there, because not only will you have killed someone, you will have woken me for no good reason. Are we clear? (Lexie raises her hand) Yes? Lexie: That was four rules. You said five. Cristina: Rule number five. When I move, you move. (awkward pause as nobody moves) Go! (Cristina's interns scramble off)

    • Richard: Now, whether you like it or not. You and I are gonna have to talk. Bailey: Chief... Richard: I know that you're angry and disappointed. Bailey: No, I'm not angry, I'm not disappointed. I'm speechless, I don't wanna talk because I'm speechless. It makes me speechless to realize that, you didn't think... I would've made an excellent Chief Resident. Richard: And you're right. You would've made an excellent Chief Resident, but you'll make an even more excellent surgeon. You belong in the OR, Bailey. Focus on honing those skills, not on how well you can juggle schedules, or fill out paper work. Believe me I know. You'll thank me for this one day. Bailey: Not today.

    Show More Quotes

    Notes (4)

    • This episode takes place 17 days after the previous episode: Didn't We Almost Have It All?

    • International Titles: Czech Republic: Měním se, tedy jsme (I am Changing Anyway I Am) Slovakia: Čas zmien (Time of Changes)

    • Original International Air Dates: Italy: Monday, December 10, 2007 on Foxlife Portugal: Thursday, December 20, 2007 on Foxlife Australia: Sunday, February 10, 2008 on Channel 7 Latin America: Monday, February 11, 2008 on Sony Entertainment Television Sweden: Wednesday, February 13, 2008 on Kanal 5 Germany: Wednesday, February 13, 2008 on ProSieben The Netherlands: Monday, March 10, 2008 on Net 5 Croatia: Monday, March 17, 2008 on RTL TV Czech Republic: May 11, 2008 on Prima Norway: Tuesday, August 26, 2008 on TV2 United Kingdom: Wednesday, September 17, 2008 on Living Romania: Tuesday, October 7, 2008 on TVR1 Thailand: Tuesday, October 21, 2008 on Star World

    • Music Featured In This Episode: 1. Breathe In, Breathe Out by Mat Kearney 2. Oversleeping by I'm From Barcelona 3. Knock 'Em Out by Lily Allen 4. 23 by Blonde Redhead 5. Reasons To Love You by Meiko 6. To Build A Home by Cinematic Orchestra

    Trivia (1)

    • A fake deer was used for all the scenes when the injured deer was lying motionless in the truck. However, they used a real animal for the brief shot of the deer standing up, magically recovered. According to associate producer Karin Gleason, Katherine Heigl (Izzie) had to sit in the truck for hours while filming, waiting for the deer to be "in the mood" and stand up for them. Heigl passed the time by reading a book, and when the deer finally jumped up unexpectedly, Heigl was ready with her character's shocked and happy reaction. Gleason has stated previously that she was very impressed with the actress's patience and performance in this scene.

    Allusions (4)

    • Cristina (to her interns): I have five rules. Memorize them. Rule number one, don't bother sucking up. I already hate you, that's not gonna change. Izzie: Traumas protocol, phone lists, pagers. The nurses will page you, you answer every page at a run. A run. That's rule number two. (notices the interns are not following her) You're supposed to follow me. Alex: Your first shift starts now and lasts 36 hours. You're grunts, nobodies, the bottom of the surgical food chain. You run labs, write orders, work every second night until you drop. And you don't complain. Meredith: On call rooms. Sleep when you can, where you can. You know, but not with anybody. Not attendings, especially not attendings. Sleeping with attendings, not a good idea. Where was I? George: Er, rule number three. If you're sleeping, do not wake you unless the patient is actually dying. Cristina: The dying patient better not be dead when I get there, because not only will you have killed someone, you will have woken me for no good reason. Are we clear? (Lexie raises her hand) Yes? Lexie: That was four rules. You said five. Cristina: Rule number five. When I move, you move. (awkward pause as nobody moves) Go! (Cristina's interns scramble off) This is a reference to the very first episode, "A Hard Day's Night" in which Bailey tells Izzie, Meredith, Cristina, and George the same thing. And Lexie, does what Meredith did. (From "A Hard Day's Night") Bailey: I have five rules. Memorize them. Rule number one, don't bother sucking up. I already hate you, that's not gonna change. Trauma protocol, phone list, pagers, nurses will page you. You will answer every page at a run. A run! That's rule number two. Your first shift starts now and lasts 48 hours. You're interns, grunts, nobodies, bottom of the surgical food chain. You run labs, run orders, work every second night until you drop, and don't complain. On-call rooms. Attendings hog them. Sleep when you can where you can, which brings me to rule number three. If I'm sleeping, don't wake me unless your patient is dying. Rule number four: the dying patient better not be dead when I get there. Not only will you have killed someone, you would have woke me for no good reason. We clear? (Meredith raises her hand) Yes? Meredith: You said five rules. That was only four. Bailey: Rule number five: When I move, you move. (looks at pager and starts running)

    • Izzie: I'm not doing it for him I'm helping Bambi. Bambi the animated story (1942 movie) of Bambi, a young deer hailed as the 'Prince of the Forest' at his birth. As Bambi grows, he makes friends with the other animals of the forest, learns the skills needed to survive, and even finds love. One day, however, the hunters come, and Bambi must learn to be as brave as his father if he is to lead the other deer to safety

    • Episode Title: A Change is Gonna Come The title of this episode is a reference to the song A Change is Gonna Come by Otis Redding. This is also a song by Sam Cooke, released in 1965. and a song by Leela James, released on her album A Change is Gonna Come in 2005.

    • Cristina: Izzie is playing Doctor Doolittle... Doctor Doolittle is a 1998 movie about a doctor that can understand animals. In it stars Eddie Murphy and Peter Boyle.

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