A Bullet for Sandoval is a part of the genre known as the spaghetti westerns, which were so-called because they were produced in Italy. The film is about a Confederate soldier, John Warner (George Hilton), during the American Civil War who deserts his unit upon learning that his lover, Rosa (Annabella Incontrera), is now carrying his child. He returns home, escaping both Confederate and Union troops, so that he may ask Rosa's father, Don Pedro (Ernest Borgnine), for her hand in marriage. But Don Pedro, a powerful rancher, despises Warner and has forbidden their marriage in the past. Before Warner can try once more, Rosa dies in child-birth. Don Pedro gives the child to Warner and tells him to leave. Warner must then protect his infant son from a cholera epidemic and Union soldiers. However, things go terribly wrong, and Warner must restore not only his pride but also the honor of his dead Rosa.