Blue Seduction follows the escapades of Mike Taylor (Billy Zane), a once famous rock musician whose life has since taken a turn for the better. In his prime, he was an alcoholic and drug user who found the error of his ways after meeting his wife, Joyce (Jane Wheeler). However, he soon finds that running from his past is a lot harder than it seems when he hires Matty (Estella Warren), a voluptuous young woman who is to be a vocalist for much of his new music. It is not long before she begins to lust for Mike and begins to lure him with his former gluttony. She pressures him to drink alcohol and do drugs and also tempts him with sex. If he is to preserve his marriage and sober lifestyle he must resist her temptations, but he will soon find that it is quite difficult to do so.