Call Northside 777, which is based on a true story, centers around the wrongful conviction of Frank Wiecek for the murder of a Chicago police officer in 1932. The story takes shape 11 years later when Frank's mother, Tillie (Kasia Orzazewski), places an ad in the newspaper offering a $5,000 reward for any information regarding the actual murderer. The newspaper's editor (Lee J. Cobb) assigns reporter P.J. McNeal (James Stewart) to investigate Mrs. Wiecek's claims. After digging into the facts of the case, McNeal believes that Wiecek is innocent of the murder. He is willing to put his career on the line against the police and the attorney's office. Not wanting to be proven wrong, they meet him with resistance at every turn, but McNeal is determined to fight for Frank Wiecek until the bitter end. Call Northside 777 tells the story of a quest for justice and the resurgence of hope for a wrongfully convicted man.