Destry Rides Again is a western film that focuses on a town in need of help. Kent (Brian Donlevy) is a saloon owner and unofficial boss of the fictional town Bottleneck. He has the town's sheriff killed when he inquires about a rigged poker game. Meanwhile, Bottleneck's mayor, Hiram J. Slade (Samuel S. Hinds), who is in cahoots with Kent, appoints the town drunk, Washington Dimsdale (Charles Winninger), as the new town's sheriff, thinking he will be easy to manipulate. What Mayor Slade does not know is that Dimsdale was a former deputy under a well known lawman. He is well aware of Kent and Mayor Slade's deceit. Dimsdale calls upon the lawman's son, Tom Destry Jr. (James Stewart), to help restore peace to Bottleneck. Tom is able to win the respect of the townspeople but shortly after his arrival, a confrontation ensues. The consequences of the confrontation will shape the town's future for years to come.