Island of Despair is a shocking 1969 film directed by Jesus Franco that details life in a women's prison of ninety-nine women on an island. The women suffer under the cruel and unkind treatment of their warden, Thelma Diaz (Mercedes McCambridge). Their horrors are only just beginning when the warden of a men's prison of five hundred men, Governor Santos (Herbert Lom), brings the two populations together. The women's prison is transformed into a brothel. The intense exploitation drives three of the women, Marie (Maria Rohm), Zoie (Rosalba Neri), and Rosalie (Valentina Godoy) to attempt an escape. They have to make their way through thirty miles of jungle and swamp that is filled with snakes in the middle of the night. A dozen of the male prisoners set out after them, and an intense chase ensues. Of course the men have to go through the same snakes and swamps, and they will wonder if their chase was worthwhile.