Jinxed! is a dark comedy set in various casinos. Willie Brodax (Ken Wahl) just lost his job as a blackjack dealer in Las Vegas. He goes to a Lake Tahoe casino for a second chance, but he isn't so lucky. Harold Benson (Rip Torn), a shady gambler, discovers that he cannot lose when playing against Willie. Harold takes advantage of his new jinx, which causes Willie to lose his job. Willie tries to start over in Reno, hoping to escape from Harold's wrath. However, this doesn't stop Harold. He takes his trailer and his girlfriend, Bonita Friml (Bette Midler), to Reno to continue his winning streak. Bonita is a wannabe lounge singer who stays with Harold despite his abusive ways. She sympathizes with Willie's bad luck. A love begins to bloom between the two "losers" and they begin to plot against Harold. Will they finally become winners in the game of life?