One Night examines the frailty of human relationships and the intimacy that develops between people who are looking for love. This ensemble cast follows fifteen New Yorkers as they descend upon a trendy New York nightclub. They include Larry (Bill Sage), a record executive who is having an affair with his young assistant Emily (Holley Fain) behind the back of the beautiful model Mia (Maria Zyrianova). Wendy (Melissa Leo), a forty something woman who wants to change her life and Greg (Christian Campbell) the nervous actor who is trying to overcome his fears and ask her out. Also at the club is Michelle (Paola Mendoza), who is meeting Jack (Michael Muhney) for the first time after weeks of chatting with him on an online dating site. All the while, Michelle's jealous former boyfriend (Billy Lush) is keeping watch on her actions. Written and directed by Michael Knowles, One Night also features Aaron Staton and Donnamarie Recco.