Stick Up Kids follows the story of four con men as they rise from poverty on the streets of Harlem to a questionable status of kings of their neighborhood. His uncle had coached Santos (Tariq Alexander) in the ways of the streets, promising him that if he used his wits he could one day escape the urban jungle. Santos and three of his friends rose through the ranks of Harlem's most wanted, pulling off everything from get-rich-quick schemes to felonies. They've reached a point in life where it feels like everything is going their way and are using their destructive talents to take care of the poor in their own backyards. But a seedy landlord is clearing out the neighborhood of truant tenants and chasing away Santos' long-time neighbors. A mysterious death brings the four together to pull off a heist that will rid the neighborhood of the interloper and reestablish their unquestioned authority.