The Runner is a gripping crime thriller that tells the story of Edward (Ron Eldard), a compulsive gambler who consistently loses at the game he so desperately loves to play. When Edward's massive debt threatens to overwhelm him, his uncle gets him a job working for a gangster and professional gambler named Deepthroat (John Goodman). Edward begins to act as Deepthroat's "runner," which entails taking his money and placing bets with different bookies. Deepthroat carefully watches every single penny that comes in, making certain that Edward has not spent any of the money on himself. Unfortunately, the temptation proves to be too great, and Edward finally slips and buys his girlfriend Karina (Courteney Cox) a beautiful ring. Once Deepthroat discovers what Edward has done, will he be able to weasel himself out of the harrowing situation, or has this player placed one final bet he simply cannot hope to win?