The Zeros follows Joe (Mackenzie Astin) as he searches for the love of his life, grade school crush Joyce (Jennifer Morrison). Joe has just learned he has only weeks left to live after being diagnosed with a rare terminal illness. The doctor says he should have died already, and there is no known cure for the disease. Instead of wallowing in his misery, Joe decides he'll take a cross-country trip to find Joyce. Armed with prescription lollipops that keep his energy up, Joe's journey takes a number of strange detours. He meets several traveling companions along the way, including Seth (John Ales), who leaves his doomsday cult to join the trip, insane ventriloquist and hitchhiker Reed (Kyle Glass), and novice stripper Fanny (Rachel Wilson). With his days numbered, Joe throws caution to the wind and tries to experience life to its fullest in this dark comedy. John Ryman directs the 2001 independent feature film.