Witless Protection features Deputy Larry Stalder (Larry the Cable Guy) as he makes an attempt to thwart a mob of gangsters that are wanted by the FBI. After making a daring rescue attempt to save the beautiful Madeleine (Ivana Milicevic), Larry learns that he just ruined a sting operation that was orchestrated by the federal agents. To make amends, he forces her along with him to Chicago in an effort to solve the case himself. Out of this contrasting partnership, a hilarious and clever comedy is born. They must use their wits to outsmart a gang of thugs and steer clear of the detectives after their botched operation. Madeleine is due in a trial which could have monumental effects on crime in the city, but she is being ruthlessly hunted down by villains in this comical film. Will they be able to get there in time to stop the outlaws? Supporting cast include Bo (Will Clinger) and Connie (Jenny McCarthy).