Seven's local police drama will not be renewed, according to media reports.
City Homicide has been axed by the Seven Network after four seasons.
This year's ratings for the drama have been challenged by a switch in time slots, tough competition and audience fatigue in the police genre.
The Melbourne-made series, in which State Police investigate inner-city murders, has been a shining beacon for Seven's drama slate since it premiered in 2007.
Across its lifetime the show has won critical praise and strong ratings.
The show was seen as a contemporary take on crime following the years of rural policing on the long-running Blue Heelers.
In its debut year it regularly attracted around 1.8 million viewers, as audiences were tempted by its brutal crimes solved by sexy but intelligent young cops.
The original cast included Hazlehurst and Bourne plus Nadine Garner, Damien Richardson, Aaron Pedersen, and Daniel MacPherson. David Field joined later, along with John Adam, Nadia Townsend, and Ryan O'Kane. Famous faces have also comprised the guest cast of killers, victims and accessories to murder.
But while some, such as Rush have won good reviews, they are not guaranteed of new seasons.
Nine's COPS L.A.C. has languished in ratings, recently moving time slots to 9:30pm -- an ominous sign in its first season. On Thursday it pulled just 487,000 viewers.
Emergency drama Rescue: Special Ops has already been renewed for 22 episodes.
Now in its third season, TEN's Rush averaged 774,000 for the first of two episodes on Thursday night. TEN is yet to declare if the show will win a fourth season.
Nonetheless, Seven has boosted its local drama slate by already announcing a new drama for 2011: Winners and Losers. With audiences waning in their interest in police dramas, Seven may well succeed with its premise of four best friends who were "losers" in high school who are about to become "winners" ten years later.
At the time of writing, Seven had not responded to a request for comment.