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Christian and Liz start their wedding preparations, and at the same time he is battling his cancer. Meanwhile, Ram trades in Kimber for a newer model, leading Kimber to go and confront Liz about her relationship with Christian.
Christian decides to employ Dr. Logan Taper for the practice, while Sean is revisited by a former client from Miami to have plastic surgery so she can attract suitors once her husband dies.
Christian relates to a patient with a unique condition whilst Sean pursues a new relationship.
In a bid to change his luck, Aidan Stone writes a biopic about Sean. Kimber wants Christian to make her daughter Jenna look younger by using Botox. A yoga instructor comes to McNamara/Troy and asks for a rather unusual procedure. Sean meets anaesthesiologist Dr. Theodora 'Teddy' Rowe.
Matt becomes envious of Sean and Raj bonding together. Christian and Liz give their relationship another chance. Raj's father pays a visit to see his son, and has a request which stuns Raj.
Sean tries to deal with his feelings for Julia, while Liz and Christian analyze their relationship and Christian meets someone who understands what he is experiencing with his breast cancer.
Sean tries to rejoin with his wrecked family, while Liz and Christian start getting closer as his chemotherapy begins to get him sick and Liz takes care of him.
Sean's physical and emotional well-being are greatly impacted after he makes it through Colleen's attack. Christian gets some disconcerting news.
Tragedy strikes the McNamara/Troy family after Julia learns what has caused her ill health. A visitor from Christian's past brings revealing news. Sean finds the price of fame to be more expensive than it's worth.
Sean experiences the ugly side of Hollywood in the form of a television critic. Matt experiences a special bond with one of Christian's patients. The cause of Julia's ailing health is discovered.
Eden looks to Sean for help after getting into business with Kimber and Ram. A group of wealthy socialites hire Christian for all of their cosmetic surgery needs. Sean discovers another side of Colleen.
Christian attempts to cope in the aftermath of a death. Colleen feels threatened when another talent agency shows an interest in Sean's acting career. The docs operate on a young man with disturbing wounds from his honeymoon.
Sean's role on Hearts & Scalpels is expanded after he takes on an agent. A suspicious Christian questions Gina's motives for moving to Los Angeles and working at McNamara/Troy.
As Julia's health worsens, Christian falls back into old habits. Sean hires Gina as the new receptionist at McNamara/Troy in order to get back at Christian. Dawn Budge returns to McNamara/Troy after another unfortunate incident which requires cosmetic surgery.
Sean discovers the secret between Christian and Julia. A hospitalized Matt bonds with his rehabilitation counselor. Eden suspiciously makes peace with Julia. Kimber and Ram reveal their future plans.
Sean tries to regain his youth through his relationship with Eden. A violent and traumatic event causes Julia to question her relationship with Olivia. In an effort to better her life, Kimber makes a decision that devastates Matt.
Jealous over Sean's new-found fame, Christian convinces Sean to tape a reality show based on their careers as plastic surgeons.
A patient inspires Sean to take his relationship with Kate in a new direction. Eden uses extreme methods to persuade Christian to perform surgery on a friend. Kimber reaches out to an former business associate when she and Matt fall on hard times.
A series of unfortunate events unfold for an unlucky Dawn Budge, who seeks reparative surgery from Sean and Christian. Annie and Eden start to form a sisterly bond, which unnerves Sean.
Sean and Julia learn more about their new family dynamic as Sean resists Eden's advances. Kate reveals a secret compulsion. Matt comes to Los Angeles with some troubling news for his fathers.
Sean and Christian learn about the glamorous side of fame and the price that many are willing to pay for it. Julia visits Sean, Christian and Liz in Los Angeles with a surprise announcement.
Sean and Christian have relocated their practice from Miami to Los Angeles. Being new to the city they find themselves having to start from scratch business wise. What they thought would naturally fall into place turns out to require some foot work. So Christian and Sean hit the town and begin discovering a whole new world.
