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During the surveillance of a suspected Synthetic front, Angela and Kurt engage in a firefight which leaves Kurt in the hospital and Angela abducted by the Synthetics. Following a tip from his old friend and mentor, Leyton Scott, Chuck learns of a rock, brought back from the moon, that is the link between the Cadre and The Sentients.
Chuck and the rest of the Odyssey 5 crew recall a riot in a Houston suburb, and the date is quickly approaching. People in the town are becoming angry, even to the point of killing loved ones -- and afterwards, they can not remember why. The rush is on to discover what is causing this rage, and how to avert the riot.
Angela is haunted by the apparent ghost of a pilot who disappeared two years ago.
The team uncovers a Sentient plot to use elementary school students in the creation of a Doomsday weapon.
When Taggart wakes up in a hospital with Paige beside him, he begins to believe that the death of his wife may have been a dream. What he doesn't know is that it is all a ruse by Dr. Bertran, who is trying to stall his activities long enough to download his consciousness into the computer.
With the still-grieving Chuck having taken off on a road trip, the rest of the crew have to deal with the synthetic that Kurt has created.
The Odyssey crew scramble to save the life of Angela's father, Senator Perry, when he's threatened by a terrifying new breed of Synthetic. Paige deals with her emotions after learning the truth about the Odyssey mission.
The O-5 team is approached by "Harry Mudd" -- a Sentient in a Synthetic body. He warns them of the imminent destruction of the world by an insane Sentient and reminds them about what's important in life.
The residents of a small town and a select group of scientists (including Mendel) are brainwashed into believing "The Lord" has specially chosen them to construct a passageway designed to bring "Him" to Earth. Taggart and Neil must reach Mendel, before it's too late.
Neil's friendly emails with a mystery woman come back to haunt him when "she" turns out to be a Sentient who is growing increasingly obsessed with him and curious about Odyssey 5. "Kit-10" wants to know the secret of the Odyssey 5 mission -- but just how far will she go to get what she wants?
Marc faces expulsion from the Astronaut Training program. Paul takes Sarah to court because of her apparently irrational obsession that their son will get cancer. Taggart suffers from the effects of a Sentient-designed virus.
Taggart, Mendel and Sarah visit a privately operated Maximum Security Prison hoping to find a clue to locating a powerful, dangerous Sentient. They ultimately find themselves trapped within a Synthetic and it's a race to the death.
Neil's friends at school are taking a new drug called "Rapture", which appears to boost their intelligence and may even promote telepathy and telekinesis. Meanwhile, a retired astronaut warns Taggart that a group called "the Cadre" have been trying for the last 20 years to get rid of manned space flight.
A mysterious being, who is not bound by time, notes that the Odyssey crew have jumped out of their proper time and comes to investigate them. It probes their minds and forces them to re-visit the personal choices they made in the most important moments of their past lives.
Neil receives an anonymous e-mail claiming that a top prosthetics researcher was murdered by the "Synthetics," who are now after the researcher's six-year-old niece, all because of a "cybiotic interface" he was working on.
Kurt tries once again to make himself a whole lot of money from his knowledge of coming events, while the rest of the team slowly start to lose their memory of the future.
The Bright Sky project schedule is moved up and Chuck must attempt to stop the launch of the satellite, while Sarah and Angela try to prevent a horrible event that happened in the original timeline.
Chuck and Kurt are looking for Professor Naran Chandra, while Angela and Sarah are investigating the "gene therapy" being conducted by Dr. Barantz. They find a woman who is willing to talk to them, and what she tells them leads them to find a specimen of living tissue that appears to have been manufactured in a laboratory.
The crew attempts to go back to their lives of five years prior to the destruction of the Earth, while also trying to begin their investigation.
The crew members of the Odyssey 5 space shuttle witness the explosion of Earth from an orbit far above. They are rescued by The Seeker and given the chance to save Earth. The Seeker sends them 5 years into the past to attempt to avert the destruction of the planet.
