In 2015, when Cole's condition worsens, Cassie seeks help from the only person who can help: Jones. In 2043, Jones and the scientists of Project Splinter are forced to rebuild their investigation.
In 2017, Cole witnesses the early days of the plague all over again. In 2043, Ramse seeks to protect his family while Jones resorts to extreme measures to gain the power core from Foster. The beginning of Cole and Ramse's involvement with Project Splinter is revealed.
Cole finds himself buried under rubble following the air strike in Chechnya. Cassie searches for Cole to confirm that the virus has been destroyed. In 2043, Jones sends Ramse and Whitley to Project Spearhead for help to retrieve Cole.moreless
Cole splinters back to 2043 and learns that history has changed because Cassie was murdered and the plague was released early. Cole must now convince Ramse and Jones to send him back.
In 2015, Cole and Cassie enter the Night Room but discover that the Army of the 12 Monkeys have found it too. In 2043, Ramse and Max try to find out more about Jones.moreless
When the West 7, Cole and Ramse's former gang, attack the facility, Cole's mission and the fate of the future are left in question.
Cole and Cassie learn that the doctor who knows the location of the Night Room died in Haiti in 2014. Cole is sent there to find him before he dies knowing that Cassie was there too and that running into her could corrupt her timeline. In 2014, Cassie goes to Haiti thinking that the outbreak there could be the virus Cole warned her about the previous year.moreless
Virologist Cassandra Railly's life is turned upside down when Cole, a time traveler from the post-apocalyptic future of 2043, arrives in the year 2013 on a mission to save mankind from a deadly plague that will eventually decimate 93.6% of the human race.moreless
Jones takes the leadership position from Amanda at The Shop, then calls Nikita and offers her and her team complete freedom by wiping away their identities and faking their deaths if they drop their mission. The team lands on a secluded Pakistan air strip, but a local drug czar and his men storm the plane and demand ten million dollars, and Nikita turns to Alex for the money. Alex removes some diamonds from a safe deposit box to make the payment, and Sam sees an opportunity to recoup his losses and considers stealing the diamonds. Meanwhile, Michael comes face-to-face with an old rival, Ramon, who hits Michael with some hard truth.moreless
Relations between the U.S. and Pakistan continue to deteriorate after Amanda plants evidence suggesting that Pakistan hired Nikita to assassinate the President. Ryan becomes increasingly suspicious of Birkhoff’s recent odd behavior and tells Nikita and Michael that he thinks Amanda may have kidnapped Birkhoff and replaced him with a double. An NSA official, Ronald Peller, gets under Birkhoff’s skin. Meanwhile, the CIA captures Alex and questions her about her involvement with Nikita.moreless
Nikita rejoins Michael, Birkhoff, and Ryan on the team’s aircraft command center. Michael refuses to discuss their relationship but tells Nikita to remain with the group until they can help her clear her name. Ryan discovers that Amanda is making doubles of important people with The Shop’s help. Nikita learns that one of Amanda's doubles has replaced the Director of the FBI, but she doesn’t know how to kill him without exposing herself. Meanwhile, Alex holds Sam at gunpoint and demands he return what he stole from her, but the two have to work togethe to escape an attack by a gang of thugs.moreless
Nikita is still on the run after she was framed for the assassination of the President of the United States. Dale, an ENN news reporter, starts to question what really happened the night of the assassination. Nikita, seeing this as a potential opportunity to clear her name, re-enters the U.S. to talk to Dale but walks right into one of Amanda's traps. Nikita's team is alerted of the problem, and Michael works to track down Nikita before Amanda finds her. While Birkhoff and Ryan assist Michael from their new mobile office, a high-tech aircraft, Alex stakes out a human-trafficking ring and discovers that The Shop is involved. She runs into trouble, and Alex is shocked when Owen/Sam arrives at the scene.moreless
Amanda places Nikita in a life-threatening situation where she has to choose between saving Michael or saving her own life. The team works to find a way to stop Amanda, but with Division diminished, they struggle to stop her plan.moreless
Nikita, Michael, and Alex pursue the black box, which has fallen into the hands of one of Amanda's agents. The remaining members of Division find themselves in danger from potential international buyers and the President, who is prepared to send the Navy SEALs to finish off Division if they cannot retrieve the box. Reformed rogue and arms dealer Cyrus returns to Division to help the team, which has no support staff, few leads, and is facing a clock ticking. With his help, Nikita, Michael and Alex stage a daring op at the tightly-secured G-20 economic summit to regain control of the box and everyone’s future.moreless
Alex, broken by Amanda’s programming, her inability to save everyone, and her role in tragic events at Division, reverts to her old behavior and lashes out violently. With most members of Division dead or scattered, Nikita and Michael try to sift through the remains of Division to determine who and what can be salvaged. To make matters worse, they must act quickly, before the President realizes what has happened. Memories of Division’s glory days haunt Nikita and Michael, and Birkhoff struggles with his own personal losses.moreless
With Nikita trapped and drugged, Amanda subjects Nikita with her horrific mental conditioning process, sharing terrible memories of her own childhood with Nikita. Through the conditioning process, Nikita uncovers Amanda’s deepest, darkest secret. With Alex's role as the leader of the mutiny now out in the open, she struggles to save everyone at Division as the violence escalates. With Michael locked up at the hands of Division members, Birkhoff and Sean work to save the women they love. Meanwhile, Owen's recent discovery of his lost memories drive him to take startling actions during Division’s lockdown.moreless
Alex admits to Birkhoff her hope of leaving Division, and Amanda starts to provide Owen with the troubling memories of his real past. Despite Nikita's efforts to help, Owen begins to confront the events of his past in the military.moreless
Nikita and Michael hear about a new prosthetic hand that could allow Michael to return to his former self, but obtaining the hand will come at a steep price. Meanwhile, Alex and Sean work to track down the agents inside Division are beind a mutiny, which ends in bloodshed.moreless
Nikita decides that Division should accept a government mission to assassinate the President of Chad while he's in Paris, but Alex disagrees with the plan and refuses to be a part of the mission. Frustrated that Nikita is keeping secrets from the rest of the group, much like Percy did, Alex asks Birkoff to dig up secrets on Danforth to use as leverage in case the government tries to shut down Division. However, Alex and Birkhoff are stunned when they uncover a secret so big it could threaten Division's existence.moreless
Amanda holds Alex captive and offers Nikita Alex's freedom in exchange for Ari's. Michael puts Nikita and Sean in charge of the prisoner exchange, but Ryan makes a last minute addition and adds Owen to the mission, leaving Michael suspicious. While captured, Alex befriends a fellow prisoner named Larissa and vows to promises to free them both from Amanda. This promise eventually conflicts with Nikita's plan, forcing Alex to choose between Nikita and her promise to Larissa.moreless
Hoping to gain control of the black box, Amanda attempts to kidnap Ari's son, Stefan, and use him as a bargaining tool with Ari. While still being held at Division, Ari asks Nikita to help protect his son. However, both Nikita and Amanda end up held captive by Stefan's bodyguard Krieg, forcing Nikita and Amanda to cooperate in order to escape. Back at Division, Owen is upset with Michael after Michael assigns Alex to help Nikita on the mission instead of him.moreless
Birkhoff receives a tip from Shadowbot on Ari Tasarov's location, and so Nikita and Owen travel to New York to detain him before the FBI catches him. They learn, however, that Ari planted the tip to set up a meeting with Nikita. He reveals that Amanda is plotting with a terrorist to carry out an attack on American soil, and he asks for fifty million dollars in exchange for information that would lead Nikita and Owen to the terrorist. Nikita and Michael are shocked when Ryan considers paying the bribe. Meanwhile, Sean is jealous of Alex and Owen's relationship.moreless
A CIA agent named Naomi comes into possession of a hard drive containing files that details Madeline Pierce's involvement with Division and delivers it to Morgan Kendrick, director of the CIA. Kendrick is killed shortly after receiving the hard drive, and Amanda frames Sean killing and the CIA takes him into custody. Nikita and Alex work to free Sean in a dangerous plan that could cost him his life.moreless
Michael officially gives up his role as a field agent and resumes his previous role inside Division running Operations. After receiving some valuable information from Birkhoff, Nikita embarks on a secret mission that takes her into dangerous territory. When Michael, Alex, and Ryan discover what Nikita has planned, they follow her into Kosovo, and the result has serious repercussions for Division.moreless