David's past comes to light as he finds a way out of his mental predicament, highlighting a powerful dynamic between him and Lenny. Lenny searches for something that she thinks David has stored away by interrogating Nurse Amy about the day that the "Man” brought David to them.moreless
David and the rest of the team find themselves back where it all started at Clockworks Psychiatric Hospital but not everyone is taking this reality at face value. Are they stuck in a dream or an alternate reality?moreless
David goes to Division 3 to recover Amy, while Cary begins to realize who--or what--that they're dealing with.
Melanie and her team try to pull David out of his own mind where he's stuck in a sedated dreamland. As they search for answers, Syd and the rest of the Summerland team wonder if they've left David's memory at all. They also realize that David has manipulated his own memories and nothing is what it seems.moreless
In the pursuit to save Amy, Melanie speeds up David's training and finds there are dark secrets hidden in his mind. As the search for answers continues, they discover David has memories within memories.moreless
Holden sends more LMDs to infiltrate the S.H.I.E.L.D. base as part of his plan to expand the Framework.
After Melanie and the others take David to Summerland, Ptonomy helps David explore his memories to learn the origins of his powers so that he can master them.
Coulson and his team try to find the captive Jeffrey before it's too late.
David Haller believes that he's insane and is placed in an institute. However, he soon suspects that he has vast telepathic and telekinetic powers... and a government agency plans to use them or destroy him.moreless
While Jeffrey and Daisy go after an Inhuman who can generate explosions, Coulson and Mack meet the woman who served as the basis for Aida's physical appearance.
When the organization behind the Watchdogs abducts Billy Koenig to get the Darkhold, Coulson and his team spring into action to rescue him and prevent the Book from falling into enemy hands.
While Aida plans a new move against the team, Melinda tries to find out what really happened to her.
Coulson and Mack learn the truth about Jeffrey after saving his life from an assassination attempt. Meanwhile, Holden continues his plan to infiltrate S.H.I.E.L.D. with his LMDs.
Aida continues her search for the Darkhold, while Coulson remains unaware of "May"'s true nature.
S.H.I.E.L.D. teams with Ghost Rider to stop Eli from destroying Los Angeles... and possibly the world.
With Ghost Rider running out of time and half of the team the gone, the others try to deal with the Darkhold.
Robbie's back story is revealed as Coulson and his team fight for their lives.
S.H.I.E.L.D. infiltrates a high-security prison to find out more about the Darkhold, while Ghost Rider fights to emerge from Robbie.
While Daisy teams up with a figure from the past to bring down the Watchdogs, Coulson and Mack square off against Ghost Rider.
While Coulson, Fitz, and Mack try to identify who is responsible for a series of blackouts, Jemma and Holden try to save Melinda, while Daisy learns more about Robbie and Gabe.
Escaped convict Luke Cage, who is trying to keep a low profile in Harlem despite his super-strength and near-invulnerability, gets drawn into danger when a pair of cousins try to take control of the neighborhood.moreless
Daisy goes back to confront Robbie, suspecting a connection between the mysterious "Ghost Rider," the ghosts, and the gangs allying together. Meanwhile, Coulson meets with the new Director while Melinda's condition deteriorates.
S.H.I.E.L.D. is legitimized again, and Coulson and Mack lead the field investigations while Melinda trains a new strike team, and Fitz and Jemma continue their relationship.
Coulson and his team take on Hive before he can set off the warhead and transform the world's population into his Inhuman slaves. However, one team member will sacrifice themselves to stop the Inhuman leader.moreless
Hive's master plan is completely revealed, forcing S.H.I.E.L.D. into action.
Talbot demands that Coulson register the S.H.I.E.L.D. Inhumans, and is less than thrilled to learn about the threat of Hive. Meanwhile, Daisy helps Lincoln to escape the base so that he can join her.moreless
While a S.H.I.E.L.D. strike team goes after Hive, Mack tries to rescue Daisy before it's too late. Meanwhile, Fitz and Jemma create an anti-toxin against Hive's parasites, and Lincoln insists on testing it on himself.moreless
Fitzsimmons tries to find a way to stop Hive as he continues to recruit Inhumans to his side.
Gideon wrestles with his past as Hive calls a meaning of Hydra's inner council. Meanwhile, Daisy and Lincoln look for a former Afterlifer with information on Hive, while the others investigate Hydra's newest business acquisition.moreless
Daisy gets a terrifying glimpse into the future and S.H.I.E.L.D. tries to prove her vision isn't set in stone.