Voyager must find a way to cross a region of space owned by a mysterious race of hostile aliens without being detected. Meanwhile, Torres and Kes must work quickly to save The Doctor when a malfunction in his program causes him to lose his memory.
During negotiations with the Karemma, the Defiant is attacked by the Jem'Hadar. After a short battle, the Defiant is left drifting in a hostile atmosphere, with Sisko critically injured. Meanwhile, the Jem'Hadar are still looking.