Alexis has been nominated for a Saturn Award in the category of "Best Supporting Actor in a Television Series" for his role as Wesley on Angel three times, in 2001, 2003, and 2004.
Alexis currently resides in Los Angeles with his wife, Alyson Hannigan. They also have homes in London and in Sacramento.
Alexis was diagnosed with Bell's Palsy just before filming of the fifth season on Angel was set to begin. So during the first episode, director Joss Whedon had to be careful to keep most of Alexis's shots on his right profile, as the left side of his face was fairly immobile at the time of filming.
Alexis is of Russian descent.
Alexis's astrological sign is Pisces and his Chinese astrological sign is Horse.
Alexis was named number three in the list of the "Top Ten Sexiest Men in the Buffyverse" in a fan poll by the Buffy the Vampire Slayer magazine in 2004.
While in London, Alexis starred in a production of "Rope" at the Chichester Theatre. Another actor in the same production was Anthony Stewart Head, who played Giles, Buffy's original Watcher, on Buffy the Vampire Slayer.
It was briefly rumored that Alexis was being considered to replace Pierce Brosnan in the role of James Bond. Either this rumor was false, or the casting people chose another actor instead.
Alexis spent three years studying at the London Academy of Music and Dramatic Art.
At the age of 13, Alexis attended the prestigious St. Paul's boarding school in New Hampshire.
The Series Finale of Angel was Alexis Denisof's 100th Episode on the series.
Alexis is 6'2" tall.
Alexis lived in London for 13 years before moving back to California. This may be the reason that he is so adept at portraying an Englishman.
Alexis has been with Alyson Hannigan since 2000. They grew fond of each other on the set of Buffy the Vampire Slayer in 1999 but Alexis wanted to keep it professional. She got her way when he moved on from Buffy to work on Angel.
They were engaged a year later, and then got married on 11 October, 2003 in California.
Alexis Denisof: (On David Boreanaz) David – funny, consistent, tough, sweet.
Alexis Denisof: (On what boarding school life was like) Well, it was a big change. I was 13 years old, and going away to school would be a change for any 13 year old – but to go from Seattle, Washington, to Concord, New Hampshire, was a big change geographically and culturally. And then also the kind of intense type academic environment that Ivy League boarding schools create was a big change. It's all at a formative time in your life, so on the one hand I treasure the time that I had there, and am very grateful for all of the values and educational opportunities it provided. It was also in some ways a shock to the system.
Alexis Denisof: It's just that there's something greater than the sum of the parts, when things are going well. That's what I like, that's what I hope to tune into when I'm working, is the sort of unknown. It's the magic part that enters a scene when the actors and the writers and the director have all done their work, and then they're able to let the magic unfold.
Alexis Denisof: It just was really a case of osmosis, and absorbing the attitudes and approaches of the people around me, and realizing that there is a place for hard work and that that should be applauded, but that simply working hard is not necessarily, in acting terms, the way to achieve a good performance.
Alexis Denisof: I mean, I was a kid. I still kind of thought maybe I'd be a professional soccer player or a fireman, or an astronaut, you know? So being an actor was pretty low on the list at that point. By the time I had finished my studies at St. Paul's School, I knew I wanted to be an actor.
Alexis Denisof: My family emigrated during the revolution. My grandfather was from outside of Moscow, and my grandmother, although some of her family were French, was from Odessa. They met as immigrants in New York in the early '20s. My mother's family came over from Ireland generations ago. That's where the silly name is from. But it's not made up! You couldn't think that one up. Mom says my father was torn between naming me Archibald and Reginald, and so I'm delighted he settled on naming me after my grandfather.