Thackery attempts a new cure in the inebriation ward; Brockhurst demands his "girls" be returned; Gallinger and his wife's relationship and Bertie's relationship with Genevieve go off in surprising directions. Later, Cornelia shows evidence of the company's wrongdoing to Henry; Barrow's marriage troubles come to a head; and Thackery performs plastic surgery on Abby.moreless
Thackery tries to steady his nerves as he prepares to separate conjoined twins before a packed audience, while Cornelia receives a surprise gift from her father-in-law and attends a charity ball for the new Knick. Later, Barrow rids himself of a threat; Opal puts a damper on the Robertsons' good mood; Algernon receives long-overdue recognition in the surgical theater, but complications arise.moreless
Edwards aids Thackery in testing out a new hypothesis. Genevieve Everidge works a story on a Thackery competitor. Cornelia is upset about the limits of Phillip's sympathies. Barrow must deal with a new adversary at Tammany Hall. While at a class reunion, a discussion of eugenics grabs Gallinger's attention.moreless
With The Knick preparing to move uptown, Edwards lobbies the hospital board to be appointed permanent head of surgery. Even with his suspension lifted, Gallinger refuses to return as Edwards' subordinate, so he heads to Cromartie Hospital in hopes of getting Thackery to return to work. Lucy tries to make amends with Bertie but has little success. Cleary looks for ways to make extra money. Ping Wu demands regular medical checkups for his prostitutes. Speight makes an effort to trace the origins of a new plague. Cornelia feeds a quarantined neighborhood in San Francisco.moreless
Shoshanna is let into a secret by Marnie and Jessa is asked for a favor by her boss. Also, Hannah gets some news.
While Jessa sets about finding a job, Hannah ropes in Elijah to help her finish an assignment. Also, Shoshanna, Elijah and Hannah go to watch Marnie perform.
Marnie starts her new job at an art gallery and Jessa is surprised by Shoshanna. Meanwhile, Hannah has concerns about her relationship with Adam.
Jessa receives an unexpected visit and the group celebrate with Adam's new friend, Desi. Meanwhile, Hannah is firstly assigned to interview Patti LuPone, who tells her that Adam's new career may have consequences, and then must review the Gramercy Park Hotel.moreless
The girls go on a weekend getaway to a Long Island beach house, where Hannah meets Elijah and invites him and his friends over.
Rocky wants to hold a baby shower, but Brian and David are against the idea, as they think they have everything they could want or need for the baby. They soon reach a compromise that they'll be no gifts but when this isn't followed, they donate all the gifts to a local children's home. Rocky and Nana team up to retrieve their gift from the home and Rocky finds something even more precious.moreless
David & Bryan get a new puppy 'Harvey Milk-Bone' to help them prepare for future parenthood, whilst Goldie and Clay reconnect in an effort to help Shania.
Now that she is alone in her flat again, Hannah hosts a dinner party, but Charlie's girlfiriend, Audrey, clashes with Marnie. Meanwhile, Jessa meets her new in-laws and Shoshanna finds she has taken her relationship with Ray to the next phase.moreless
Marnie renews her acquaintance with an annoying artist and Hannah makes a new friend.
Elijah starts to question his sexuality, resulting in hum sharing a secret with Marnie, who finds that she must compromise on her career expectations. Meanwhile, While Hannah receives some attention from Adam and Jessa finds she enjoys being a wife.moreless
Jessa returns to New York fresh from her honeymoon, to find Hannah throwing a party to celebrate moving in to her new home. Meanwhile, Marnie receives some bad news and Shoshanna does her best to avoid Ray.moreless
Bryan and David discuss their future and how big they want to grow their family and later play cupid for Gary by setting him up with Bryan's ex-boyfriend and legendary party boy Monty (guest star Matt Bomer),but their plan leads to more than they bargained for. And Rocky and Jane again find common ground when they help Shania with some mean girls.moreless
David and Bryan try to make their home safer for their upcoming baby. Jane reveals a kinder side of herself due to eggnog, and after attending a holiday party with Bryan, she tries to settle into the real estate market of Los Angelos.moreless