Skye must make a decision about her powers, while Coulson finds himself going up against... S.H.I.E.L.D.
The team deals with the revelation of Skye's altered nature, while Bobbi and Mack tell Lance where their true allegiance lie. Meanwhile, Grant and Agent 33 go on a personal mission.
To expose S.H.I.E.L.D.'s supposed crimes to the world, Cal gathers a team of "super-villains" and lures Coulson back to his hometown. Meanwhile, Melinda brings in her ex-husband to help evaluate Skye's psychological condition after her recent transformation.moreless
After a battle, Lady Sif finds herself on Earth with amnesia, and turns to S.H.I.E.L.D. for help. Meanwhile, Bobbi and Mack continue their own operation within the team, risking exposure.
John returns to Ivy University to help one of the Newcastle crew, Ritchie. Ritchie's TA has performed a ritual that has given a killer from another reality access to four of Ritchie's students... and the killer is picking them off one by one.moreless
John summons a demon to possess him and save his life from the invunche and Anne Marie's gunshot wound. However, the demon threatens to take over John's body and Anne Marie, Chas, and Zed race to exorcise it before it's too late.moreless
Coulson and his team prepare to destroy the Kree city, but learn where Whitehall and his people are drilling in and go to take them on. Meanwhile, Skye meets her father for the first time, and he reveals his plan to get revenge on Whitehall for killing Skye's mother.moreless
Zed's visions and the scry map led her and John to a preacher who can heal injury. John soon discovers that the healing comes with a terrible cost... and finds a fallen angel stranded on Earth.moreless
Coulson and half of the team head to San Juan to enter the Kree city, while the other half go to Vancouver to keep Raina from falling into Hydra's hands. However, Grant is one step ahead of them.moreless
Papa Midnite inadvertently raises the dead, who set out to kill the living. To stop them, he must join forces with John and put spirits to rest.
While Coulson's team tries to track down the secret, they meet the Doctor. Meanwhile, Bobbi interrogates Sunil and Ward kidnaps his older brother.
John travels to Atlanta to stop a demon that an old friend has inadvertently risen... and learns that he may have to sacrifice a great deal to stop it.
Someone is killing people and leaving the alien writing etched on the corpses. As Coulson's team pursues the murderer, they discover a connection to their director's past.
John and Zed travel to Chicago to investigate the death of a record producer, and discover that a voodoo priest named Papa Midnite is seeking a 45 LP that has recorded the Devil's voice.moreless
John travels to Heddwich, Pennsylvania to stop guardian spirits who are killing the locals. When he arrives there he meets Zed Martin, a young woman who is drawn to John by her visions.moreless
Hydra impersonates S.H.I.E.L.D. and launches an attack on the UN to turn the world against Coulson and his people. As they rush to find the source of Hydra's new weapons, Coulson negotiates with the American Senator spearheaading the efforts to destroy S.H.I.E.L.D.: Grant's older brother Christian.moreless
After a botched exorcism that condemns a young girl to Hell, demonologist John Constantine tries to forget. But a message from an old friend summons him to help a woman who demons want to see destroyed. As he helps the woman, Liv, John is approached by an angel who wants him to serve the forces of Heaven.moreless
An undercover Jemma finds herself the subject of a security crackdown by Hydra's security chief, Bobbi Morse. Meanwhile, Raina tries to negotiate with Coulson to get the obelisk before Whitehall has her killed.moreless
Coulson and Melinda go undercover to obtain a painting that may hold the answers to Coulson's attacks. Meanwhile, Fitz fights his own problem to help the team when the Bus is sabotaged, while Whitehall forces Raina to bring him the obelisk.moreless
In the season finale, Jack discovers the alarming depth and scope of the organization to which he's lost Amy. Meanwhile, Marcus and Madison engage in a fatal struggle; and Richard is forced to go on the run, but he recruits an unexpected partner along the way.moreless
Jemma puts her cover as a researcher for Hydra at risk to stop her new organization from acquiring Donnie Gill, a Gifted who could prove valuable to both sides. Meanwhile, Fitz confronts Grant for the first time since Grant tried to kill him.moreless
Jack makes a last attempt to bring Amy home, after making a gruesome discovery in his backyard. Meanwhile, Rose remains haunted by a tragedy; and Gary realizes how to expose the corruption behind Qui Reverti but it will require a great sacrifice.moreless
While Coulson and his team try to stop Hydra from getting the obelisk from Creel, Talbot continues his pursuit of the fugitives. Meanwhile, Mack reaches out to Fitz, while Lance must consider his future after he loses his friends.moreless
Coulson and his team go underground to continue the fight against Hydra. Besides dealing with the American government's attempts to capture them, the team must track down a World War II artifact of amazing power.moreless
Madison's instincts gain strength as she begins to make sense of Marcus' memories; Jack gets a terrifying confession out of Gary; Richard comes face-to-face with Marcus.