While Coulson's team tries to track down the secret, they meet the Doctor. Meanwhile, Bobbi interrogates Sunil and Ward kidnaps his older brother.
John travels to Atlanta to stop a demon that an old friend has inadvertently risen... and learns that he may have to sacrifice a great deal to stop it.
John and Zed travel to Chicago to investigate the death of a record producer, and discover that a voodoo priest named Papa Midnite is seeking a 45 LP that has recorded the Devil's voice.moreless
Hydra impersonates S.H.I.E.L.D. and launches an attack on the UN to turn the world against Coulson and his people. As they rush to find the source of Hydra's new weapons, Coulson negotiates with the American Senator spearheaading the efforts to destroy S.H.I.E.L.D.: Grant's older brother Christian.moreless
After a botched exorcism that condemns a young girl to Hell, demonologist John Constantine tries to forget. But a message from an old friend summons him to help a woman who demons want to see destroyed. As he helps the woman, Liv, John is approached by an angel who wants him to serve the forces of Heaven.moreless
An undercover Jemma finds herself the subject of a security crackdown by Hydra's security chief, Bobbi Morse. Meanwhile, Raina tries to negotiate with Coulson to get the obelisk before Whitehall has her killed.moreless
Coulson and Melinda go undercover to obtain a painting that may hold the answers to Coulson's attacks. Meanwhile, Fitz fights his own problem to help the team when the Bus is sabotaged, while Whitehall forces Raina to bring him the obelisk.moreless
In the season finale, Jack discovers the alarming depth and scope of the organization to which he's lost Amy. Meanwhile, Marcus and Madison engage in a fatal struggle; and Richard is forced to go on the run, but he recruits an unexpected partner along the way.moreless
Jemma puts her cover as a researcher for Hydra at risk to stop her new organization from acquiring Donnie Gill, a Gifted who could prove valuable to both sides. Meanwhile, Fitz confronts Grant for the first time since Grant tried to kill him.moreless
Jack makes a last attempt to bring Amy home, after making a gruesome discovery in his backyard. Meanwhile, Rose remains haunted by a tragedy; and Gary realizes how to expose the corruption behind Qui Reverti but it will require a great sacrifice.moreless
While Coulson and his team try to stop Hydra from getting the obelisk from Creel, Talbot continues his pursuit of the fugitives. Meanwhile, Mack reaches out to Fitz, while Lance must consider his future after he loses his friends.moreless
Coulson and his team go underground to continue the fight against Hydra. Besides dealing with the American government's attempts to capture them, the team must track down a World War II artifact of amazing power.moreless
Madison's instincts gain strength as she begins to make sense of Marcus' memories; Jack gets a terrifying confession out of Gary; Richard comes face-to-face with Marcus.
Gary learns something very strange about Amy, which suggests a larger, more terrifying conspiracy. Meanwhile, Madison arrives in Seattle and threatens an old acquaintance; Rose puts pressure on Richard; and Jack and Gary find a reliable source.moreless
Jack searches for Amy in Seattle, but her movements produce more questions than answers. Meanwhile, Madison finds herself in a train station with a ticket to Seattle, an envelope with money, and a mysterious key; and Richard suffers serious consequences due to an act of humanity.moreless
Nolan fights to save the planet from the arkbrain's terraspheres under Irisa's control. However, E-Rep--and Amanda--are willing to kill Irisa to stop her rather than risk all on Nolan's plan. Meanwhile, Pilar abducts Christie and Alak, forcing Datak and Stahma to rescue Rafe and go after them.moreless
Members of a secret society chase immortality by seeking refuge in the bodies of others. In the opener, the wife of a retired cop vanishes on her way to Seattle on business. As her husband searches for her, he is asked by a friend to help with a murder case. Meanwhile, a 9-year-old girl starts behaving erratically after seeing a stranger on a beach; and an assassin desperately tries to stop his secret from becoming known.moreless
A deadly mine collapse leaves Amanda and Niles trapped, and it's a race against the clock for Nolan and Rafe to save them. Meanwhile, Irisa convinces Tommy to help her steal a terrasphere, while Rafe learns that Quentin has made a deal to free Pilar.moreless
When Nolan and E-Rep arrest a VC terrorist in Defiance and try to determine the location of a bomb, the terrorist's compatriot calls Amanda and tells her to free the man... and claims to have her missing sister Kenya.moreless
A dead Castithan hand maiden shows up on Datak's doorstep, her eyes removed, and he turns to Rafe for help. Meanwhile, Irisa meets the man from her visions, and Alak discovers that Christie is going to the Janus club behind his back.moreless
An Arkfall crash salvage mission led by Nolan leads to danger in the form of an alien race he has never encountered before; at the same time, Stahma makes a shocking power play after she's admonished by church elders for her growing sense of female empowerment; and Irisa begins confessing her deep, dark secrets to Tommy.moreless
A stalker comes after Amanda, raising concerns for both Nolan and Niles.