A sick airline passenger is taken to the hospital. As Alex performs emergency surgery on the passenger, she believes the patient may be infected with a deadly and contagious virus.
Fear and doubt strike Joel in the OR, so Kinney takes him on a therapeutic trip to where she is originally from, then they try to rescue a woman who's pinned under a truck. Elsewhere, Charlie connects with a deceased therapist; and Alex cares for a fitness buff with a rare condition.moreless
Charlie is removed from the ventilator. It is discovered that a patient who arrives for a routine follow-up could hold the key to understanding Charlie's condition.
Dawn and Alex bicker over who will make decisions for Charlie. Charlie meets with a prisoner that has died in the spirit world.
Alex is performing a routine surgery when it takes a turn for the worse after the patient falls into a coma. Charlie connects with the patient and Alex gets personal with a case.moreless
When a hypnotist is called into the hospital to help with a patient who can't remember his identity, the man uses his psychic ability to connect Charlie and Alex.
A double hand reattachment gives Alex a chance to prove that she is still capable of being chief surgical resident. Maggie thinks a homeless man received the wrong diagnosis.
An exhausted Alex treats a hockey player while working the nightshift in the ER.Charlie must fight hard for his life when he comes down with pneumonia.
Alex must treat a patient who already has had multiple surgeries.
Alex treats a boy with mysterious symptoms and Joel and Maggie must help a patient despite his religious beliefs.
When stadium security guard Gil Collins defies Sgt. Parker and risks his own life by taking a hostage situation into his own hands, he complicates matters and draws Team One into a complex situation where nothing, especially his motive, is a it first seems.moreless
Bonnie warns Elena about Stefan. Tyler attempts to humiliate Stefan but it backfires as Stefan catches and passes the ball back, winning everyone over. Damon and Caroline gate crash any plans Elena had for Stefan and Bonnie to get along.moreless
Mystic Falls begins the preparations to celebrate the passing of a comet. Vicki recuperates in the hospital from her injuries. Stefan uses his abilities to erase Vicki's attacker from her memory, but is interrupted by Matt. Mr. Tanner warns Aunt Jenna about Jeremy. Elena and Damon meet for the first time at the Salvatore house and his revelation on Stefan's past brings Elena closer to the truth. Damon finds his next victim in Caroline.moreless
Elena Gilbert and her brother Jeremy come to terms with the death of their parents. Elena is popular amongst her peers and the perfect straight A student, but has difficulties hiding her grief from the world. Meanwhile, Jeremy treads on a dangerous path of using drugs to ease his pain. The arrival of new student Stefan Salvatore, however, makes Elena think about romantic possibilities.moreless
A former client of Dean's calls him up when a plane crashes under mysterious circumstances. Dean and Sam must board an endangered flight to save the other passengers.