To get to Zambia to gather leopard DNA and cure the outbreak, the team turns to an animal rights activist to escape the U.S. ahead of the authorities.
Once Mitch tells them that Delavane is working for Reiden, the team try to get their story out via Jamie's friend in the press. Meanwhile, Jackson and Chloe pay Delavane a visit, and Mitch and Abraham deliver the stolen medication to Clementine.moreless
The team goes to an American tourist island in Massachusetts to investigate an outbreak of rats that have already killed the crew of a cargo ship. Meanwhile, Mitch pays Clementine a visit and then prepares to trade the Mother Cell for his daughter's cure.moreless
The team investigate a bear attack in France, and Chloe reunited with her ex-fiancé. Meanwhile, Mitch discovers the next evolutionary step of the mutated animals, while the team prepares to hack Reiden's mainframe after Jamie is accused of Ben's murder.moreless
In Rio, Abraham tries to track down his friends, who are stalling for time with Gustavo. Meanwhile, Jackson and Ben find Jamie after the crash, and set out to find Evan Lee. In France, a woman is subject to a bizarre home invasion.moreless
While Mitch, Chloe, and Abraham travel to Rio de Janeiro to stop the government's bat extermination program, Jackson, Jamie, and Ben try to find a chemist who can connect Reiden to the animal attacks.moreless
The team travels to Mississippi and investigates the wolf attack on the prison. Mitch and Abraham try to capture a wolf, while Chloe, Jackson, and Jamie search the prison and meet FBI agent Ben Shaffer.moreless
While Jackson and Abraham travel to a remote island to find Robert's research, Jamie convinces Mitch to go to New Orleans with her to present the case against Reiden. Meanwhile, wolves launch an attack on a prison, and Gaspald shows Jamie the crime scene in Slovenia.moreless
Jackson rescues Abraham and talks with the local doctor--his mother Elizabeth--who confirms that the lions killed their victims as slowly and painfully as possible. In Slovenia, a British couple adopt a young boy and take him to the circus to see the tigers. And in Paris, Chloe meets with a mysterious man who offers her answers.moreless
Two fatal lion attacks, thousands of miles distant, are the first indications of a threat that could wipe out all humanity.
Phillip Stroh is back and demands a new deal in exchange for information regarding a current, horrific murder.
Priscilla fights her way back to reality with the help of Aaron and Rachel. Trueman's atrocities escalate as he tries to stop the resistance. Bass and Miles kidnap the President.
With his wife and son now dead, Neville joins with Bass to seek his revenge on the patriots. Rachel finds out about Priscilla, and Miles and Charlie pinch a steam train.
Charlie finds Miles and Truman gets his shot to get Miles and Bass.
Miles gets injured fighting off a bunch of Sheriffs and then gets inadvertently trapped in a dilapidated building making his way back to camp. Tom kidnaps Charlie and discovers the truth about Jason.moreless
After receiving inside information from Jason, Miles and Monroe head to Austin to try and sabotage the Patriots' plans. Aaron becomes concerned over Priscilla's odd behavior.
Monroe makes a jolting attack on the Patriots while Gene and Miles look for potential allies in Willoughby. Neville and Jason find themselves in deep water when Doyle finds out about the poison. Aaron and Priscilla press onward.moreless
The town of Willoughby has been turned into a reeducation facility, and Doyle makes things difficult for Tom.
Aaron awakes from slumber to find himself back in his previous life, in a world with power. Something however, is not quite right.
Connor and Monroe are forced to fight to the death.
With his wife held captive, Tom is ordered be President Davis to hunt down and kill Monroe. Meanwhile, Monroe, Charlie and Miles head off on a risky mission to new Vegas, to hire some mercenaries from one of Monroe's previous, but dodgy acquaintances.moreless
Miles, Rachel and Bass kidnap Truman and infect him with typhus that the Patriots have engineering to persuade him to give up the location of the antidote.
Monroe has to make a choice about his son, while Neville and Julia continue to take things carefully, which annoys Jason. Meanwhile, Gene shows Charlie an unexpected sight.
Miles, Monroe and Rachel head to Mexico to look for Miles' son.
Miles, Rachel and Charlie continue their search for Aaron.
Aaron's experience with death attracts interest. Miles and his compatriots attempt to escape. Rachel and Gene's personal problems impact Charlie. Meanwhile, Neville takes his chances with the Patriots.
Rachel uncovers some worrying facts, and shares a moment of rapport with Charlie. Meanwhile, Neville and Jason continue to struggle with their relationship.
Monroe continues to be useful but is captured by The Patriots and sentenced to death.
Texas Ranger John Fry comes to town who may be the only man capable of taking down The Patriots.
Monroe saves Charlie from a potentially nasty encounter, but Charlie refuses to give him an inch of trust. Miles and Rachel start planning a resistance movement against the Patriots. Neville deals with a problem regarding his boss.moreless