Brent was a boyhood friend of former Major League pitcher Dave McNally.
He worked alongside Connie Chung doing local Los Angeles newscasts during the early 1970s.
In November 2006, an action figure of himself was released as part of the Rocky II series of figures.
He has a "down-home" manner of speaking, often addressing his viewers as "folks" or "partner," such as, "Folks, here's your third down and 10" and "Now hold on, partner... there's a penalty."
He is regarded as the first broadcaster to apply the term "March Madness" to the annual NCAA Men's Basketball Championship Tournament.
Brent provided his voice for the play-by-play commentary for the 2000 Konami video game ESPN NBA Tonight.
Some of the words and phrases Brent frequently uses during his telecasts are included in "The Brent Musburger Drinking Game," including: "The Pardner," "Folks," "It's a foot race!" and "There's that man again."
Brent was an umpire for Minor League baseball during the 1950s.
He attended Northwestern University's Medill School of Journalism in Evanston, Illinois.
Brent appeared in the movies: Rocky II, The Main Event, The Waterboy, and Mickey, as a play-by-play commentator.
Brent: Last year, I thought the Big Ten (Conference) was unfairly put down and very underrated. Interestingly, this year, I happen to think they're a little overrated only because I don't see a marquee team stepping out, like an Illinois last year.
Brent: Austin, Texas and Columbus, Ohio are the two toughest communities in which you have to put together a winning football team. They are both big metropolitan areas without professional football and major league baseball to sidetrack them.
Brent: I hate Lou Dobbs with a passion. He is my mortal enemy. If I find him, I will destroy him. He owes me 15 dollars.