Brian was the voice of Crocco in Cartoon Network's first original feature film Re-animated which premiered December 8, 2006 and combines live action with animation.
Brian has a guest role as Stevie, the medical examiner for a two part episode of Comedy Central's hit police parody Reno 911!. In the first part, "Son of a Chechekevitch" he initially believes Sheriff Chechekevitch died from a poison delivered orally, but later upon further investigation, he concludes he instead died of a peanut allergy. In the second part of the episode, "The Investigation Continues", Stevie is arrested for being under the influence of medicinal marijuana.
Brian did the voice of Jim Kuback in the short lived WB animated series, Mission Hill. Brian achieved cult status for his role after the show was given renewed popularity thanks to being picked up by Cartoon Network's Adult Swim.
Brian wrote the song, "Ass-Kicking Fat Kid" with Scott Ian of the legendary metal band, Anthrax for the comedy, Run Ronnie Run.
Brian co-authored a comic book series for Image Comics called The Last Christmas, which features Santa delivering presents and killing mutants in a post-apocalyptic world.
Brian has an official profile on MySpace and also has an updated blog at his own website.
Brian is a fan of classic horror films as well as the films Phantasm, Halloween, Chainsaw, Dawn of the Dead, Return of the Living Dead, Cat's Eye, and Grizzly.
Brian has had notable guest appearances in many sitcoms such as Seinfeld, Friends, Everybody Loves Raymond, NewsRadio, The Bernie Mac Show, and Method & Red.
Brian plays Tank in the 2002 comedy, Run Ronnie Run.
Brian has an uncredited part as a man seated at Table #9 in the 1998 Adam Sandler comedy, The Wedding Singer.
Brian is 6'7".
Brian appears in the metal band Anthrax's music video, "What Doesn't Die".
Brian is a self-proclaimed nerd - he enjoys comic books and also dubs himself as a "metal nerd".
Brian is the voice of the character Brian in the Star Wars parody PC game Star Warped.
Brian plays Jimmy in Rob Zombie's 2005 horror film, The Devil's Rejects, the sequel to The House of 1000 Corpses.
Brian has a heavy metal band called POSEHN. The band's lineup is a who's who of the hard rock elite, featuring Scott Ian (Anthrax), Joey Vera (Armored Saint), John Tempesta (White Zombie, The Cult) and Brian himself on vocals.
Brian's comedy album, Brian Posehn - Live In: Nerd Rage, originally released independently, was picked up for redistribution by the extreme metal label Relapse Records. In addition to his stand up routines, the album also features two songs, one of them by his heavy metal band POSEHN.
Brian has most recently surfaced on The Showbiz Show with David Spade in a segment called The Nerd Perspective.
Brian had a brief appearance as "himself" alongside Sarah and Laura Silverman in 2005's Sarah Silverman: Jesus Is Magic.
Brian was the messenger who delivered the manuscript in which Joey's soap opera character "Dr. Drake Ramoray" is killed off on Friends.
Brian appeared in the 2003 movie, Grind as a customer at the store Chili 'n Such, the fast food restaurant that the main characters work at in the beginning of the movie.
Brian has a recurring role as the voice of Tom Peters' friend Gibbons the midget on Adult Swim's animated comedy, Tom Goes to the Mayor. Due to the animation style of the show which involves taking photos of the cast with different expressions, and then filtering them so they resemble mimeographs made of only blue and white, Gibbons' appearance is Brian's actual head placed on a midget's body.
Brian played the gas station attendant in the 2003 movie prequel, Dumb and Dumberer: When Harry Met Lloyd.
Brian is a graduate of Sonoma Valley High School.
Brian: (about being approached by Relapse Records to reissue his album) They got it. Even though they had never done comedy before, they had an idea about how they were going to get this record out there. They've been kicking ass. It's been a dream to see me reviewed in metal magazines. It's so cool. I'm doing an interview with Kerrang soon.
Brian: (about being in Rob Zombie's film The Devil's Rejects) My scenes were with (Bill) Mosely and (Sheri) Moon, who were fucking amazing, and Geoffrey Lewis (Eastwood's sidekick) and Priscilla Barnes (the third blonde on Three's Company). I was surrounded by real actors and I'm such a fucking lucky clown.
Brian: (about comic book titles he follows) I always read The Walking Dead. I love Civil War, where that's going. The reveal (by Spider-Man of his secret identity to the rest of the world) kinda scared me. It was kinda weird. But I always have a three or four issue rule with a new series. I love the new Ed Brubaker Daredevil.
Brian: (about if he feels typecast as the same roles) I've played weird mail boys, surly convenience store clerks and slightly retarded people. All over the map, I'd say. What other roles am I gonna get? I'm fine playing weird guys that work at menial jobs. I want to start doing it in dramas.
Brian: If you had told me in 1984 that I was going to shoot a video with Anthrax in twenty years, I would have kicked you in your dick and pushed you back into your time machine.