Christina founded the Right Action for Women organization to help women at high risk for breast cancer.
Christina has a Dachshund-mini Doberman mix dog named Tallulah.
In August 2008 it was revealed Christina had been diagnosed with breast cancer through a routine breast test. She is following her doctor's treatment and is expected to make a full recovery.
In 2001, Christina was given "special thanks" in the credits of the film Donnie Darko.
In 1999, Christina won the TV Guide Award in the category of Favorite Star of a New Series for her role on the television series Jesse.
In 1987, Christina won the Young Artist Award in the category of Exceptional Performance By a Young Actress in a New Television, Comedy or Drama Series for her work on the television series Heart of the City.
In 2008, Christina won (along with David Faustino) the TV Land Award in the category of Siblings That Make You Grateful for Your Own Crazy Family for her role on the television series Married with Children.
In 1992, Christina was nominated for an MTV Movie Award in the category of Most Desirable Female for her role in the 1991 film Don't Tell Mom the Babysitter's Dead.
In 1998, Christina was honored with the President Award at the Ft. Lauderdale International Film Festival.
In 2008, Christina was nominated for an Emmy for "Outstanding Lead Actress in a Comedy Series" for her role on Samantha Who.
Christina was mentioned in the 1991 song, "Set Adrift on Memory Bliss" by PM Dawn.
While starring in Jesse, Christina appeared in 2 of NBC's public service announcements The More You Know. Her topics were drug abuse and sexually transmitted diseases.
In 2006, Christina appeared in the music video, "A Public Affair" by Jessica Simpson and in 1990, she appeared in the music video, "Rattlesnake Kisses" by Electric Angels.
Christina's father, Robert Applegate, is a record company executive, her mother, Nancy Priddy is a singer and actress.
In 2006, Christina appeared in a commercial for Hanes.
Christina quit school when she was 17 years old.
Christina supports People for the Ethical Treatment of Animals(PETA).
Christina is 5' 5" (1.65 m).
Christina was among the attendees at the 2004 Emmy Creative Arts Awards.
Christina's debuted on Broadway in the play titled, Sweet Charity, in which she played Charity. It ran on Broadway for nine months before closing.
Christina enjoys books about spirituality.
Christina was nominated for "Best Performance by an Actress in a TV-Series: Comedy/Musical" at the 1999 Golden Globe Awards for her role in Jesse.
Christina ranked #60 in VH-1's 100 Greatest Teen Stars [February 2006].
Christina has an apple tattoo below her navel, a vine on both ankles and a tattoo of her mom's name and the name of her church.
Christina is a vegetarian.
Christina first appeared on television as an infant in a commercial for disposable diapers.
She went to high school with Milla Jovovich.
Christina was chosen as one of People Magazine's, "50 Most Beautiful People" in 1999.
Christina resides in Laurel Canyon, LA in a Tuscan-inspired home.
Christina started dance lessons at the age of five.
In 2003, Christina won an Emmy Award for Outstanding Guest Actress in a Comedy Series playing Amy on Friends: The One with Rachel's Other Sister.
In 2004, Christina was nominated for an Emmy Award for Outstanding Guest Actress in a Comedy Series playing Amy on Friends: The One Where Rachel's Sister Babysits.
Christina met her husband, Johnathon Schaech, through director Gregg Arak. The two were married in 2001, separated in 2005 citing "irreconcilable differences", and their divorce was finalized on August 10, 2007.
Christina: (about the upside of having a double masectomy) I don't have to wear a bra! They don't hang down to my knees like they used to. They just hang up there. They're pretty solid. They're not going anywhere. And "the gals" look good in tank tops, and they didn't before!
Christina: (on having breast cancer) Yes, it's hard. It sucks. But I'm not a victim. I started looking for a beach house the day I found out I had this little disease. You just kind of go, 'What are you waiting for to get the things that you want and the things you dream of?
Christina: (on being given a clean bill of health after her successful mastectomy) I'm clear. Absolutely 100 percent clear and clean ... so I'm definitely not going to die from breast cancer. [Before surgery] I was just shaking and – and then also immediately, I had to go into ... 'take-care-of-business-mode'.
Christina: I improvised something in [the 2002 film] The Sweetest Thing that I was really proud of. I'm sitting behind this kid at a church wedding, and I'm trying to get him to turn around and not look at me because I'm not suppose to be there. So, I go, "Look, there's Jesus.' It got the biggest laugh at the premiere.
Christina: (about having played keyboard in Tina Yothers' band in an episode of Family Ties) It was so stupid. I'm more sorry about the clothing and the hairdo. If I had put on anymore shoulder pads, I could have been a football player. It was an ugly-a*s thing. So, I'm really sorry about that-- not for anybody else. I'm just sorry for myself.
Christina: My dream is to have a house on the beach, even just a little shack somewhere so I can wake up, have coffee, look at dolphins, be quiet and breathe the air.
Christina: Every single kid in my group of friends at school was from a single-parent family.
Christina: But men and women, getting along, it's a joke. We have completely different brains, it's a completely different thing.
Christina: My first acting job was playing a drug dealer when I was nine. My one line was 'It's really good sh*t, man.' That's the '70s for you.
Christina: (On having to quit school) It's one of those choices that I can honestly say was a big mistake. I wish I had a better knowledge of history and the other things I could've learned. Of course, nothing is stopping me from learning now. In fact, I'm probably better prepared.
Christina: It was not easy for my mother, being a struggling actress and raising a child. We were these two sort of vagabonds, never knowing where the money was going to come from. She always says she couldn't afford a babysitter, which is why she put me on the stage.
Christina: I started doing radio commercials for Kmart when I was 4. They had to splice all my consonants together because I couldn't talk very well. But these jobs helped my mother and me put food on the table. It took the two of us working.
Christina: (On becoming a TV star in her teens) I wasn't one to go out and buy a new car and stereo system and expensive clothes. My mom helped keep me grounded.
Christina: I've always been shy and sort of vulnerable. My mom says that when she would drop me off at school, I'd stand back and check out the situation - see if it was safe before I'd join the other kids.
Christina: (On her sitcom Married... with Children) The show definitely shocked and disgusted people. But, privately, they enjoyed laughing at it. I think all too often people look at the perfect families on television and think 'Why can't my family be like that?' In the case of "Married... with Children," people were able to say, 'Thank God my family's not like that!'
Christina: The person who I have my child with is going to be the right person. I don't want to raise a child by myself. I could do it. But I definitely don't want to. I want to be a mother who has the original father there. And I want to be with that person until I'm 80 years old, sitting out on the porch with our glasses of lemonade, laughing about our lives.
Christina: There are a lot of sacrifices a mother makes when she's raising a child by herself. I saw it when I was growing up, watching all my mother did for me. But it wasn't until recently that I fully understood the price she paid because of how we had to struggle.
Christina: (On accepting her role in the sitcom Jesse) This was a major commitment. I really had to sit and think about it. I eventually came to the conclusion that it came into my life for a reason.