Chicago Med is inundated with the victims of shooting at a movie theater, the shooter and the hero. Dr. Rhodes gets irritated by the general consensus that he should not try too hard to save the shooter's life, a teenage boy. Sharon Goodwin must manage the press and the internal dynamics of the situation. Dr. Manning treats a teenage girl, Ashley, for nausea and feels that there is concerns to consult Dr. Charles for a possible eating disorder. Dr. Charles employs an unusual method which raises concerns with both Dr. Manning and the patient's mother. Dr. Choi is asked to consult on a case involving a elderly woman who makes very racist statements.moreless
When Dr. Rhodes treats a man who was impaled, he reunites with his estranged sister, Claire and takes a look at his past. Dr. Halstead treats a young musician who needs surgery but it could cost her the ability to hear.moreless
Dr. Choi must put his personal feelings aside when treating a teenage mother who abandoned her newborn baby in an alley. Dr. Manning treats the abandoned baby and clashes with Dr. Choi about the mother. Dr. Charles assists Sarah Reeves in treating an elderly woman diagnosed with Dementia.moreless
The new team of doctors have a hand full when there's a train accident.
Malcolm engineers Slade's escape to train Oliver and Thea in how to survive. Meanwhile, five years ago Amanda brings Oliver and Maseo to Starling City to recover the Omega bio weapon, and Oliver must decide whether to stop China White or stay with his friends and family who are falling apart without him.moreless
Religious motives are suspected in a couple's murder. Meanwhile, Laura and Jake look for a new nanny and encounter a familiar face in their search.
Oliver and his team look for Sara's killer and the trail leads to an assassin, Komodo, who is methodically eliminating his targets. While they hunt down the killer, Roy tells Oliver why Thea isn't returning his phone calls. In the past, Maseo informs Oliver that he has to kill Tommy Merlyn.moreless
Carrie catches an elusive assassin but then is forced to trust the woman when it is revealed she has vital information that could prevent a terrorist attack on New York City.
Root intersects with the team again when the Machine gives Finch the Number of a janitor after it sends Root to investigate the man.
After a battle with Cyrus Gold, Oliver is poisoned and left for dead, and Felicity gives him an antidote that causes hallucinations of his past. Meanwhile, Brother Blood captures Roy, Barry continues assisting Felicity, and Lance loses someone when he tries to run surveillance on Cyrus.moreless
When they discover Malcolm's plan, Oliver and Diggle try to stop him but lose Felicity to a police arrest. Meanwhile, Thea learns that Roy is in danger and goes to The Glades, endangering herself as well, while Oliver risks what's left of his friendship with Tommy for the sake of honesty. In the past, Oliver, Shado, and Slade try to stop Fyers from bringing down a passenger jet.moreless
The Dark Archer visits a seismologist to further The Undertaking. Meanwhile, Laurel makes a decision after Tommy tells her the truth, and Roy and Thea try to find The Hood. In flashback, Fyers tells the captive Oliver, Shado, and Slade of his plans for the missiles and for Yao Fei.moreless