Dr. Linus Creel is studying patients with a specific DNA-gene. He triggers them to do violent acts. Red informs the team about the pattern of the violent acts but they have to find out who the bad guy is for themselves this time. Meanwhile Red pressure Frank Hyland to start a new life with his wife.moreless
Abbie and Ichabod must find a way to save Abbie's sister, Jenny, who has been possessed by an evil spirit.
While attempting to communicate with Katrina in Purgatory, Ichabod and Henry Parrish unwittingly unleash a new evil.
The Machine gives the team a new Number: Simmons, the corrupt HR officer that murdered one of their own. Meanwhile, Finch tries to stop a friend from going too far in their quest for vengeance.moreless
Jessica Barnes, the daughter of wealthy parents, enters rehab for drug abuse. While there, she turns 18 and, against doctor's orders, leaves to join a farming commune. She also begins to withdraw large sums of money from her six-figure trust fund, giving it to the farm's leader. Stark & Rowan intervene to end the flow of funds and to get her out of the commune. Meanwhile, Martina confronts Tommy about rumors that he helped her get her job.moreless
Linda helps out Danny and Kate when she overhears important information related to their shooting case. Jamie is determined to track down the person who attacked Henry at an ATM.
Hank and Divya treat a large-animal veterinarian. Evan and Paige comfort a close friend who's experienced an unexpected loss. Boris is obligated to make accommodations.
Unbeknownst to his family, Frank must deal with a potential biological weapon's attack on New York City as they celebrate Mother's Day. Danny and Jamie's long standing dispute comes to a head.
'Marilyn' Director Derek Willis makes the two potential leads jump through hoops for the ultimate role of Marilyn Monroe. Julia and her husband find new roadblocks in the road to adoption, and Eileen struggles to keep 'Marilyn'financially viable in the midst of her strenuous divorce.moreless
Will's judicial bribery case goes before a grand jury.
Lockhart Gardner represents a patient in a case against Patti Nyholm over a liver transplant, but ends up working with her after she fires her firm. Meanwhile, Alicia has to deal with the fallout of the news about Kalinda and Peter's affair.moreless
Lovejoy meets distant cousins from America, who are visiting England.
As well as a female ghost, old Lord Wakering has treasures which once belonged to Sir Walter Raleigh, and both Lovejoy and Mary-John Lovejoy, his American cousin, want them. Some of Lord Wakering's things are stolen, and Lovejoy travels in hot pursuit to the Carolinas, where he is not made welcome. Charlotte has to fly over to get him out of trouble.