John and Zed return to New Orleans after Corrigan asks for their help finding a missing girl. Meanwhile, the Brujeria put a bounty on John and Papa Midnite sets out to collect it in return for his sister's soul.moreless
Manny helps John investigate a mysterious attack that leads them to a hospital. When Zed attempts to gain a vision, she has a seizure and discovers that continuing to help John may threaten her life.moreless
John returns to Ivy University to help one of the Newcastle crew, Ritchie. Ritchie's TA has performed a ritual that has given a killer from another reality access to four of Ritchie's students... and the killer is picking them off one by one.moreless
Chas faces a parent's worst nightmare when thousands of people across Brooklyn slip into a mysterious coma, including his own daughter; and it's up to John to figure out how to awaken the victims of this evil force.moreless
Zed's visions and the scry map led her and John to a preacher who can heal injury. John soon discovers that the healing comes with a terrible cost... and finds a fallen angel stranded on Earth.moreless
Papa Midnite inadvertently raises the dead, who set out to kill the living. To stop them, he must join forces with John and put spirits to rest.
John travels to Atlanta to stop a demon that an old friend has inadvertently risen... and learns that he may have to sacrifice a great deal to stop it.
John and Zed travel to Chicago to investigate the death of a record producer, and discover that a voodoo priest named Papa Midnite is seeking a 45 LP that has recorded the Devil's voice.moreless
John travels to Heddwich, Pennsylvania to stop guardian spirits who are killing the locals. When he arrives there he meets Zed Martin, a young woman who is drawn to John by her visions.moreless
After a botched exorcism that condemns a young girl to Hell, demonologist John Constantine tries to forget. But a message from an old friend summons him to help a woman who demons want to see destroyed. As he helps the woman, Liv, John is approached by an angel who wants him to serve the forces of Heaven.moreless
Leonardo and Riario find that entering the Vault of Heaven is not as easy as they may have hoped. Meanwhile, Lorenzo becomes embroiled in Ferrante's games and Lucrezia meets the Turk.
As Leonardo tries to cross the Atlantic, without the aid of maps, Lorenzo's makes an undercover trip to Naples. Meanwhile, Lucrezia attends a secret meeting at the Vatican.
While Pope Sixtus's sanctions against Florence forces Lorenzo to make sacrifices, Leonardo continues to search for the Book of Leaves and Lucrezia seeks out new allies in Rome.
When Pope Sixtus tries to unite powers against Florence, Leonardo must come up with a solution. Meanwhile, Riario continues to tempt Nico.
With the House of Medici weakened, the Pazzis try to seize power in Florence, leading to Leonardo making a desperate gamble. Meanwhile, Count Riario believes he is getting closer to the Book of Leaves.moreless
Leonardo attempts to save the Medicis when he learns of a Pazzi conspiracy to seize power in Florence. Meanwhile, Lucrezia makes a confession and the Turk reveals where the Book of Leaves can be found.moreless
In order to gain entrance to the Vatican, Leonardo must somehow travel through the sewers, underwater. Once inside, he not only encounters the mysterious prisoner, but also comes face to face with Sixtus IV. Meanwhile, back in Florence, Giuliano unmasks the traitor who has been spying for Rome.moreless
Piero and Lorenzo leave to meet the Duke of Urbino, in the hope of securing military assistance against Rome. Meanwhile, Leonardo journeys to Romania in his quest for the Book of Leaves and encounters 'Vlad the Impaler'. Back in Florence, Giuliano's search for the true spy continues.moreless
Piero represents Leonardo when he faces trial for the accusations against him. Meanwhile, Lorenzo tries to impress some prospective royal clients and The Turk returns to Florence.
Leonardo reveals his latest weapon to Rome's army, but is later arrested. Meanwhile, Becchi awaits his punishment after being accused of spying for Rome.
When the Medicis receive the blame for an outbreak of demonic possession at a convent, they task Leonardo to investigate. Meanwhile, Riario challenges a mysterious prisoner.
The spectacular failure of his new musket causes a rift between Leonardo and the House of Medici. Meanwhile, the Pope's nephew arrives in Florence and the search for the elusive the Book of Leaves continues.moreless
In 15th Century Florence, the ruling House of Medici commissions a young Leonardo da Vinci to create both a spectacular display for the Easter celebrations and some innovative war machines. Meanwhile, Leonardo encounters a mysterious Turk.moreless