In 2001, David was nominated for a Blimp Award at the Kids' Choice Awards in the category of Favorite Voice from an Animated Movie for his role in the 2000 film The Emperor's New Groove.
In April 2007, a mutual friend introduced David to Nicky Whelan, one of the stars of the Australian series, Neighbours. David flew Nicky from Australia to Los Angeles to appear in an episode of his show, The Showbiz Show, and as a return of the favour, he will make a cameo appearance on Neighbours.
He was brighter than his second-grade classmates, and took advanced math and reading.
He is very sensitive to light. The combination of bright lights on-set and working under sunlight while filming Black Sheep caused permanent damage to his eyes.
He says the coolest people he had ever worked with or met are Bono from U2, Sean Penn, Kid Rock and Eminem.
He was in an elementary school class with Brad Pitt.
He hosted both the Teen Choice Awards and SpikeTV's Video Game Awards in 2003.
In 1989 The 13th Annual Young Comedians Show Hosted by Dennis Miller brought David Spade solo attention.
He has been romantically linked to several female celebrities including Krista Allen, Caprice Bourret, Julie Bowen, Lara Flynn Boyle, Sara Foster, Teri Hatcher, Kristy Swanson and Heather Locklear.
He was one of the guests at Lindsay Lohan's 19th birthday party.
He has a tattoo of cartoon character Calvin, from Calvin and Hobbes, on his left bicep. The tattoo artist was actor Sean Penn.
He has been commercial spokesman for Sierra Mist soda and Capital One credit cards.
He was attacked with a stun gun by his personal assistant, David "Skippy" Malloy, and then robbed in November 2000.
He was offered a chance to replace Joan Rivers's Fox talk show.
He suffers from hypoglycemia.
He was going to be in the George Wendt role in The Naked Truth.
He graduated with a degree in business from Arizona State University in 1986 and is a member of the Sigma Alpha Epsilon fraternity. Other famous SAE alumni include former President William McKinley, golfer Bobby Jones, actor Fred Savage, and recording artist Nick Lachey.
He went to Saguaro High School, graduating in 1982. In April of 2006, The Sabercat, the school's paper launched a story on alumni of the school, including a small section on him.
His father, Wayne Spade abandoned his family when David was six. Judy Todd eventually remarried, but David's stepfather committed suicide in 1980. David was 17 years old at the time.
He grew up in Scottsdale, Arizona.
In 8 Simple Rules for Dating My Teenage Daughter, Patrick Warburton guest stared while David Spade was a main character. In the new movie Kronk's New Groove, David Spade has a small role while Patrick Warburton had the role of the main character.
He was not in the original pilot of Just Shoot Me. The show was rejected until his character was added.
He was charged by police in his home state of Arizona for reckless jet-skiing in 2001.
He was very good friends with the late actor Chris Farley.
He is 5'6½ (1.66 m) in height.
During his first season as a writer on Saturday Night Live (1989-1990), he appeared on-screen exactly three times. He was not credited as a cast member until the next season.
He once worked as a skateboard shop employee.
David: I can see getting married and having a family, because it is the next thing on the agenda. You can only do this for so long. I'm old, and my friends all have kids. And I'm single, still blow drying my hair!
David: I have to wear a hat even indoors and flashes in particular freak me out. I even have to make them turn down the lights in the make-up trailers. I've become such a pain in the butt with this light-sensitive thing, it's a wonder they don't just shoot me. On his light sensitive condition.
David: I was a somewhat bright child, which led to different sorts of problems. In second grade, I moved up to fourth grade math and reading. There was an option to skip a grade but I was so tiny and microscopic that my mom was, like, 'He has enough now, let's not make his life totally terrible.' I stayed in my grade but alienated everyone by being, like, 'brainiac.'
David: (to Heather Locklear) I'm just lucky to know someone that's that sweet and pretty.
David: Success? You can't get a big head about it. When people stare at me, they could be whispering to their friend, 'That guy sucks! Have you seen him before? He's horrible.
David: I've been with a beautiful girl from time to time.
David (On why he chose not to attend actor/friend Chris Farley's funeral): I just couldn't have gone into a room where Chris was in a box.