A plague strikes down the residents of Defiance. The people blame the Irathients and place them under quarantine, while Nolan and Connor must confront the E-Rep soldiers to get the cure.
Irisa has a vision that a Razor Rain storm is coming toward Defiance. While Nolan warns the townspeople, Sukar is seemingly killed... and then comes back to life and asks Irisa to help him on a holy mission. Meanwhile, Nicky tries to find out what happened to Birch, and Stahma asks Kenya for assistance teaching Alak how to pleasure his bride-to-be.moreless
Two Defiance residents are killed under mysterious circumstances, and Nolan soon confirms that that they were torn apart by mutant Hellbugs. Meanwhile, Irisa is plagued by visions from the past, and Datak and Stahma try to reconcile the situation between Christina and Rafe so that her marriage to their son can proceed as planned.moreless
The team tries to help a young man with amazing memory who is taken hostage to help get to a weapon with "smart" bullets which can shoot a target even behind cover. The situation gets complicated when Ed himself is taken hostage.moreless
With the rookies on their own during a turbulent night in the station, a prisoner pulls a gun on Chris. IA's inquiry into the incident leaves the rookies thinking about the choices they made that led to that night's events and about the fine line between telling the truth and having each other's backs. Meanwhile, Gail it still trying to recover from her traumatic kidnapping. And while Chris is caught unaware by a surprise, Andy learns a secret about Nick's past.moreless