Sam and Dean convince Crowley to help them track down a rogue hellhound. Meanwhile, the angel Kelvin approaches Castiel with an offer to rejoin Heaven.
The British Men of Letters have Mary bring in Sam to witness them wiping out every vampire in America. However, things go wrong when the hunters become the hunted and the vampires come after them. Meanwhile, Fetch approach Dean on his own to persuade him that the Men can give dean what he needs.moreless
Three teachers turn up dead, and Sam and Dean discover that a ghost is involved... and it died on the ship that was to take Gavin to America. Meanwhile, Kelly meets a demonic benefactor.moreless
The Men of Letters ask Mary to perform a special mission for them, which involves her recruiting Sam, Dean, and Castiel without their knowledge of who she now works for. The mission soon goes south and Castiel is mortally wounded.moreless
When Dean starts losing his memories of everything, Sam turns to Rowena for help.
Sam and Dean travel with Castiel to help him investigate the murder of several angels that he worked with when he was a warrior angel. They soon discover that a woman is seeking vengeance and will stop at nothing to kill Castiel and his remaining assoicates.moreless
Sam and Dean must find a way to escape the black site where the government has imprisoned them. Meanwhile, Castiel and Samantha find themselves at loose ends with no idea where the brothers are or if they're even alive.moreless
Sam and Dean try to trap Lucifer, but discover that he's found a near-perfect hiding place: the President of the United States.
Lucifer plans to use his host body, Vince Vincente, to gather an army of fans and bend them to his will. Sam, Dean, Castiel, and Crowley try to track him down and stop him before it's too late.moreless
Sam and Dean attend the wake of a Hunter, Asa Fox, who got his start in the business after Mary saved his life. After Mary arrives, the Winchesters soon discover that one of the other Hunters is a killer.moreless
The one survivor of the Roanoke House massacre stands trial for murder, and must face Lana Winters in a one-on-one interview.
Nazi necromancers attempts to bring back Hitler's spirit from the pocket watch that it's trapped in, and only the Winchesters can stop them.
A trio of fans of the series make a pilgrimage to the Shaker House... during the Blood Moon. Meanwhile, Audrey and Lee try to find Monet and the camera, and Dylan's rescue proves short-lived.moreless
Sam and Dean investigate two mysterious deaths that suggest demons were responsible. The trail leads them to a devout religious family that harbor a dark secret.
Lucifer takes over the body of a rock star. Meanwhile, Dean, Castiel and Mary try to rescue Sam, but Dean is uncomfortable with putting Mary in danger, even though she insists on going along.moreless
Dean is reunited with Mary and Castiel, and they search for the missing Sam... unaware that the Men of Letters are torturing him for information on the American Hunters. Meanwhile, Crowley searches for Lucifer, who is leaving a trail of burned-out bodies in his wake as he jumps from person to person.moreless
After three people are killed in a tow yard Major Crimes has to catch the culprit before he kills again. Rusty is trying to find the way how to run a fingerprint evidence on Buzz's investigation.moreless
Two British tourists get attacked during a Venice Beach robbery. An English journalist exploits their tragedy, in turn jeopardizing Los Angeles' big-bucks tourist industry. Also: Rusty's biological mother tries to make amends with him over her pregnancy.moreless
When Flynn shows Provenza and Buzz the house he is thinking of buying for him and Sharon they find a body in the pool.
FBI asks LAPD's help to find a body of a soldier who was decapitated by ISIS supporter on video.
LAPD Sex Crimes' detective is found murdered at the house belonging to a film company that produces adult movie videos. Buzz is still working through his father and uncle's murder files. Rusty hears some unexpected news about his mother.moreless
Homeless shelter volunteer Amanda Pond disappears while distributing hygiene packages. Buzz goes through unsolved old murder case of his father and uncle. Flynn thinks about selling his house and moving closer to Sharon and his daughter.moreless
With the fate of the universe in their hands, Sam, Dean, Castiel, Crowley, and Rowena come up with a desperate plan to kill Amara. However, one of them must sacrifice their existence to do so.moreless
God finally meets with the Winchesters, but he's not what they expected. Meanwhile, Amara requests a meeting with Dean, and the Winchesters set out to rescue Lucifer so that he can help God reimprison God's sister.moreless
Sam and Dean travel to a town in Colorado where a fog is spreading the same madness that they ran into when they first encountered Amara. Meanwhile, Metatron is summoned to a meeting with God.moreless
The Winchesters team up with two other hunters to take on the chitters, cicada spirits who possess humans so that they can reproduce.
While the Castiel-possessing Lucifer tries to take control of Heaven, Sam and Dean hear out Crowley on his plan to stop Amara.
Sam and Dean take on a pair of werewolves... and one of them manages to kill Sam. When Dean gets back to civilization, he kills himself in a desperate attempt to ge a Reaper's attention and make a deal to bring Sam back to life.moreless
The new owners of a house accidentally break a seal, unleashing a creature that Bobby and Rufus trapped several years ago. Now Sam and Dean are working the same case, and have to save a new wave of coma victims before their bodies wither and die.moreless
Conclusion. A video wire elicits admissions, as seven murders are tied together and suspects are narrowed down to three, in the Season 4 finale. Also: Mark Hickman faces the truth about his past; and Provenza and Patrice resolve wedding issues.moreless