Dean falls increasingly under the spell of the First Blade. Meanwhile, Metatron makes his move against humanity, as Sam, Castiel, and Gadreel try to stop him.
Castiel calls on the Winchesters to help when his army of angel followers are attacked, and Dean is all too eager to help under the First Blade's influence.
Charlie finds Miles and Truman gets his shot to get Miles and Bass.
While Sam and Dean help Castiel interrogate one of Metatron's angels, Abaddon takes extreme measures to force Crowley to help her against the Winchesters.
Miles gets injured fighting off a bunch of Sheriffs and then gets inadvertently trapped in a dilapidated building making his way back to camp. Tom kidnaps Charlie and discovers the truth about Jason.moreless
In Chicago, Sam and Dean encounter five clans of monsters that run the city's underground... and Ennis, a young would-be hunter who seeks revenge on one of the clans.
Sheriff Mills calls in Sam and Dean when a prisoner under her protection is abducted by vampires.
Metatron tries to get Castiel to join forces with him. Meanwhile, Sam and Dean capture Gadreel.
After receiving inside information from Jason, Miles and Monroe head to Austin to try and sabotage the Patriots' plans. Aaron becomes concerned over Priscilla's odd behavior.
Sam goes to check out a report of peaceful people transforming into violent killers and discovers a connection to a case involving his grandfather. Meanwhile, Dean deals with the aftermaths of acquiring the Mark of Cain and Crowley is eager to take advantage of his weakness.moreless
Monroe makes a jolting attack on the Patriots while Gene and Miles look for potential allies in Willoughby. Neville and Jason find themselves in deep water when Doyle finds out about the poison. Aaron and Priscilla press onward.moreless
Crowley starts taking human blood again and Abaddon learns of his search for the First Blade. To find the Blade before the Knight of Hell does, Sam and Dean enlist the help of a former Man of Letters.moreless
The town of Willoughby has been turned into a reeducation facility, and Doyle makes things difficult for Tom.
Aaron awakes from slumber to find himself back in his previous life, in a world with power. Something however, is not quite right.
Sam and Dean travel to Washington to investigate the death of a young girl, only to discover that Harry and Ed, the Ghostfacers, have arrived before them.
Connor and Monroe are forced to fight to the death.
While Castiel falls into the hands of Bartholomew and his faction of angels, Sam and Dean make a startling discovery about the Men of Letters bunker... and a special captive that Abaddon's demons are holding.moreless
With his wife held captive, Tom is ordered be President Davis to hunt down and kill Monroe. Meanwhile, Monroe, Charlie and Miles head off on a risky mission to new Vegas, to hire some mercenaries from one of Monroe's previous, but dodgy acquaintances.moreless
Miles, Rachel and Bass kidnap Truman and infect him with typhus that the Patriots have engineering to persuade him to give up the location of the antidote.
Crowley and a reluctant Dean go on a road trip to find The First Blade, the only weapon that kill their mutual enemy, Abaddon. Meanwhile, Castiel proposes to use Gadreel's remaining grace in Sam to track the angel, but warns that it could cause Sam permanent damage.moreless
Monroe has to make a choice about his son, while Neville and Julia continue to take things carefully, which annoys Jason. Meanwhile, Gene shows Charlie an unexpected sight.
In the wake of Kevin's death, Castiel proposes a plan to Dean to help Sam retake control of his body from Gadreel. However, they have to turn to Crowley for help.
Miles, Monroe and Rachel head to Mexico to look for Miles' son.
Sam and Dean investigate an angel slaughter and discover that Castiel is already looking into the matter. The individual responsible captures Castiel, while Dean wonders whether ti's time to tell Sam the truth about Ezekiel.moreless
When four members of the same church chastity group disappear, Sheriff Jody Mills calls in Sam and Dean for help. However, Dean soon disappears and Sam and Jody have to go after him.moreless
Miles, Rachel and Charlie continue their search for Aaron.