Sam and Dean track down a demon prostitution ring which leads them to the witch Rowena. They go after her, unaware that Cole is still on Dean's trail. Meanwhile, the husband of Hannah's host body comes looking for his wife, complicating things for Hannah and Castiel.moreless
Sam tries to cure Dean and remove his demonic essence, but discovers that his brother doesn't want to be cured. Meanwhile, Crowley realizes that he will need someone to rally the forces of Hell behind to maintain their loyalty, and seeks out a dying Castiel.moreless
Crowley discovers that Dean is becoming increasingly difficult to control, and contacts Sam to make a deal. Meanwhile, Sam escapes from Cole and returns to his hunt for his brother, and Hannah tries to make a deal with Metatron to save Castiel's life.moreless
Dean embraces his new life as a demon and hits the bars with Crowley. Meanwhile, Sam tries to track down his brother, unwilling to accept what Dean has become, and runs afoul of a man trying to get revenge on Dean for a past crime.moreless
Dean falls increasingly under the spell of the First Blade. Meanwhile, Metatron makes his move against humanity, as Sam, Castiel, and Gadreel try to stop him.
Castiel calls on the Winchesters to help when his army of angel followers are attacked, and Dean is all too eager to help under the First Blade's influence.
Metatron tries to get Castiel to join forces with him. Meanwhile, Sam and Dean capture Gadreel.
The killer: Ian; the victim: Kevin Carpenter.
Detectives Flynn and Vega investigate the death of Carpenter, who returned to the city after spending three years traveling through the Far East. A cryptic note, “I never had the courage until now,” is found in the hotel room where the victim died. Meanwhile, Angie is upset that Sgt. Kevin Cross, someone with whom she has history with, is the new team leader after the recent promotion of Boyd Bloom to Superintendent.
Elizabeth has to put on Coal valley Founder’s Day, Jack helps the only coal mine survivor accept what happened to him help his family also come to terms with it.
Kennex and Dorian investigate a suspected homicide at a hospital of a man who knew his exact time of death before he experienced his fatal cardiac arrest, connected to a black market for bio-mechanical organs which can be remotely shut down and resold. Meanwhile. Dorian connects with one of his decommissioned "brothers".moreless
Following Charlie's death, Jimmy's crew become nervous and Max makes progress on the missing money. Meanwhile, Grace and Mitch find that a dead Treasury agent may be linked to Sam's death.
An Alzatraz guard reappears who, although basically a good guy, is being asked to do bad things.
A man named Sylvester asks Chloe for help but ends up getting attacked and killed. Clark is led to the former headquarters of the Justice Society of America where he meets up with Dr. Fate, Hawkman, and Stargirl. Later, Clark, John Jones, Green Arrow, and Chloe team up to help the JSA stop the killer before he murders someone else in the group. Meanwhile, Lois receives a package from a mysterious agency called Checkmate.moreless
A woman takes hostages on Cloud Nine and demands that Adama turn over Sharon in order to avenge her husband's death at the hands of the Cylons.