Mitch and Jamie try to disrupt Davies' plans and are helped by two unexpected allies. Meanwhile, Jackson and the others meet with Robert's sponsors in Pangaea and try to develop a cure.
Jackson, Jamie, and Mitch return to the bunker to recover the stolen serum after the Shepherds' betrayal... but one of them won't be coming back out.
While Mitch and Jamie work together when animals attack the Russian embassy, Robert provides an explanation to Jackson as Davies' people close in on the jet.
While Mitch and Abe try to find Jackson, Allison and Jamie meet with the Russian Minister of Defense and try to convince him to withdraw his country from the Noah Objective.
Mitch and Allison contact Mitch's father Max, a cryptozoologist who can help them date the last set of bones. Meanwhile, Abe faces a difficult decision after Elizabeth mutates and attacks Jackson.
Jackson learns that his mother Ellizabeth has gone missing and demands that Allison sends a rescue team. Before she can, Davies leads an assault on the plane to capture Jackson.
While Mitch and Jackson try to recover a clue to the cure from Jackson's memories, the others head to New England to follow a new lead.
After reuniting with Jamie, the team travels to Portugal to obtain some jellyfish venom in search of a cure for the animal mutation. Meanwhile, Jackson's mutation begins to endanger his teammates.
Jamie and Logan finally reach Caraquet but discover that it's not what they expected.
The team has to infiltrate a Reiden black-tie party to recover a sloth with the new mutation, and discover what Davies' plan is to wipe out the mutated animals. Meanwhile, Jamie continues her trek to civilization.moreless
The team heads to New Brunswick to rescue Jamie and the leopard cub that holds the potential cure to the mutation. Meanwhile, the mutation spreads to insects and hundreds are killed in DC.moreless
The team travels to Argentina to make contact with a fellow researcher and find an amazing discovery. Meanwhile, Jamie tries to make her way to civilization and meets a stranger on the road.moreless