Coulson and Gonzales are forced to join forces with an unreliable ally to defeat Hydra.
While Skye meets a fellow "Inhuman," Coulson takes on Gonzales for the future of S.H.I.E.L.D.
Secrets from Ellis Grey's past come to light. Maggie makes a shock announcement and Callie continues to work on the Veteran's Project.
Coulson and his team--what's left of it--go all-out to stop HYDRA. Meanwhile, Fitz and Simmons try to escape a watery grave, and Grant begins to question Garrett's sanity.
Coulson's team goes undercover against HYDRA to learn their true plans... and Grant's connection to them.
Agent Maria Hill returns to help Coulson as what's left of S.H.I.E.L.D. collapses due to the efforts of HYDRA.
Garrett and Triplett return to help track down the Clairvoyant, who sends Deathlok to stop them.
Coulson and his team go undercover aboard a train to try and get a lead on the Clairvoyant.
Centipede's interrogation of Coulson helps him uncover information about his death and mysterious resurrection... but at the potential cost of a teammate's life.
Coulson recruits a former enemy, Mike Peterson, to help the team take on Centipede, but they soon find themselves under threat from an unexpected quarter.
In the aftermath of the Avengers' battle in New York City, the world attempts to come to grips with the presence of superheroes, gods, and aliens in their midst. Agent Coulson is resurrected under mysterious circumstances and forms an elite team of agents from SHIELD to keep track of a secret organization known as The Rising Tide. Meanwhile, they must deal with other menaces, such as a man who suddenly finds himself with vast uncontrollable power.moreless
Oliver and his team go after Deadshot, only to discover that ARGUS plans to capture the assassin... and recruit him as an operative. Meanwhile, Roy seeks out The Hood while Laurel inadvertently drives a further wedge between Oliver and Tommy. And on the island, Shado teaches Oliver how to use the bow.moreless
Emily struggles to decide whether she should start a relationship when Will learns about their situation and starts to jealous. Emily and Tyra treat an unruly patient, but after learning of the woman's hoarding situation at home, Emily starts to think that the woman's personality changes may be caused by her cats. After Cassandra and Will's break-up, Will is distracted by Cassandra's strictly professional behavior and misdiagnoses a patient. Meanwhile, Micah's sister comes to visit after learning the truth about their mother.moreless
Pete helps Myka catch a dangerous killer--the man who murdered her previous partner. Meanwhile, Artie, Claudia, and Steve interrogate a dog that is a key witness to the theft of an artifact.