Becca and the two men in her life combat escalating emotional tension as they try to flee Europe; Dax learns who his enemies are.
The residents determine their future as they make their final decisions regarding post residency positions; Mark admits to Derek that he is torn between his love for Lexie and the fact that Julia can give him everything he's ever wanted; Ben plans something extra special for Bailey, but she is preoccupied with her work; and Arizona encourages her childhood friend, Nick, to have surgery. Meanwhile a couple on their third honeymoon come to the hospital complaining of mysterious symptoms.moreless
The residents agonize over their oral boards, reliving every answer they gave during their exams; Arizona's close childhood friend comes to Seattle Grace for medical help; the doctors work on a patient who is missing one third of his skull; and Julia asks Mark to start a family with her. Meanwhile Catherine tells Richard that one of his residents has failed.moreless
Former CIA agent, now a florist, Becca Winstone (Ashley Judd) learns that her son Michael (Nick Eversman) has disappeared while studying abroad in Rome, Italy. Also stars Sean Bean asBecca's late husband Paul, whom Michael watched die ten years earlier.moreless
For her new assignment Annie has to convince smugglers to hire her. Meanwhile, Henry Wilcox is invited back by Joan and Arthur.
After escaping his handlers an Iranian trade delegate approaches the CIA to cut a deal. In exchange for entry into the United States, he is willing to hand over stolen intelligence.
When national security is threatened, Annie searches to find the leak in the Senate Intelligence Committee. Meanwhile, Auggie starts working as his old unit's handler.