The team deals with the revelation of Skye's altered nature, while Bobbi and Mack tell Lance where their true allegiance lie. Meanwhile, Grant and Agent 33 go on a personal mission.
To expose S.H.I.E.L.D.'s supposed crimes to the world, Cal gathers a team of "super-villains" and lures Coulson back to his hometown. Meanwhile, Melinda brings in her ex-husband to help evaluate Skye's psychological condition after her recent transformation.moreless
After a battle, Lady Sif finds herself on Earth with amnesia, and turns to S.H.I.E.L.D. for help. Meanwhile, Bobbi and Mack continue their own operation within the team, risking exposure.
While Jemma secures the Kree city, Skye is put into quarantine. Meanwhile the team carries out an operation against Hydra to eliminate the people who arranged Trip's death.
Peggy is cornered. Meanwhile, the SSR closes in on Howard Stark.
The SSR arrests Edwin after tracing Howard's car from the Roxxon explosion. Meanwhile, Peggy continues her pursuit of Leviathan.
After World War II is over, Peggy finds life as a glorified secretary for the SSR boring. When Howard Stark is framed for the sale of his weapons to the enemy, he asks Peggy to help him recover them and prove his innocence.moreless
Peggy pursues Brannis and the missing bombs, and Jarvis insists on helping her. Meanwhile, the SSR gets photos of the mystery blonde seen with Spider and speaks with Hugh Jones, the owner of the imploded factory.moreless
Coulson and his team prepare to destroy the Kree city, but learn where Whitehall and his people are drilling in and go to take them on. Meanwhile, Skye meets her father for the first time, and he reveals his plan to get revenge on Whitehall for killing Skye's mother.moreless
Coulson and half of the team head to San Juan to enter the Kree city, while the other half go to Vancouver to keep Raina from falling into Hydra's hands. However, Grant is one step ahead of them.moreless
While Coulson's team tries to track down the secret, they meet the Doctor. Meanwhile, Bobbi interrogates Sunil and Ward kidnaps his older brother.
Someone is killing people and leaving the alien writing etched on the corpses. As Coulson's team pursues the murderer, they discover a connection to their director's past.
Hydra impersonates S.H.I.E.L.D. and launches an attack on the UN to turn the world against Coulson and his people. As they rush to find the source of Hydra's new weapons, Coulson negotiates with the American Senator spearheaading the efforts to destroy S.H.I.E.L.D.: Grant's older brother Christian.moreless
An undercover Jemma finds herself the subject of a security crackdown by Hydra's security chief, Bobbi Morse. Meanwhile, Raina tries to negotiate with Coulson to get the obelisk before Whitehall has her killed.moreless
Coulson and Melinda go undercover to obtain a painting that may hold the answers to Coulson's attacks. Meanwhile, Fitz fights his own problem to help the team when the Bus is sabotaged, while Whitehall forces Raina to bring him the obelisk.moreless
Jemma puts her cover as a researcher for Hydra at risk to stop her new organization from acquiring Donnie Gill, a Gifted who could prove valuable to both sides. Meanwhile, Fitz confronts Grant for the first time since Grant tried to kill him.moreless
While Coulson and his team try to stop Hydra from getting the obelisk from Creel, Talbot continues his pursuit of the fugitives. Meanwhile, Mack reaches out to Fitz, while Lance must consider his future after he loses his friends.moreless
Coulson and his team go underground to continue the fight against Hydra. Besides dealing with the American government's attempts to capture them, the team must track down a World War II artifact of amazing power.moreless
Coulson and his team--what's left of it--go all-out to stop HYDRA. Meanwhile, Fitz and Simmons try to escape a watery grave, and Grant begins to question Garrett's sanity.
Coulson's team goes undercover against HYDRA to learn their true plans... and Grant's connection to them.
Agent Maria Hill returns to help Coulson as what's left of S.H.I.E.L.D. collapses due to the efforts of HYDRA.
The life of Coulson's true love is threatened by HYDRA and the team has to undertake a perilous mission to save her. Meanwhile, Grant tries to get close to Skye and convince her to decrypt the hard drive, but discovers that there's an unexpected complication.moreless
Col. Glenn Talbot pursues Coulson's team as they begin to uncover S.H.I.E.L.D.'s darkest secrets.
Coulson and their team must deal with a traitor within and an organization that distrusts them.
Garrett and Triplett return to help track down the Clairvoyant, who sends Deathlok to stop them.
When Lorelei goes after the male members of the team, the female members get an assist from a god: Lady Sif of Asgard.