The team heads to Cuba to hunt down a possible spree killer after the bodies of American victims are found in multiple areas.
The killer: Robin Gould; the victim: Geoff Armstrong
Robin is an architect who works for a firm run by her fiancee Isaac Griffin and Geoff is an urban planner who works for the city and teaches scuba diving in his off time. Detectives Flynn and Vega are first called in to investigate the disappearance and presumed murder of Robin, who, two days earlier, had called off her engagement. Robin's car is found in a remote area containing her blood. During their investigation, the team talks to Isaac concerning his missing ex-fiancee and discover a connection to Geoff, who is responsible for granting a variance from the city to allow construction on one of Isaac and Robin's prize developments to proceed. Meanwhile, Vega struggles with his upcoming weapons re-certification test.
As Kyle gets worse, Soren takes the team to the Bleeding Tree. At the Abbey, Peter learns about Michael's breeding program, and Julia offers a new idea how to grant Amy immortality in exchange for Mother.moreless
Julia arrives at the Island along with Sergio where they meet Peter at the Abbey. Meanwhile, Alan, Kyle and Lt. Winger go into the woods searching for what may be a cure for the pathogen.moreless
After being stung by a bee, a worker gets sick, leading Kyle to investigate the bees. Meanwhile, Sarah looks for the child who recovered and Peter calls Balleseros for further instructions. In the future, Julia and Hatake get into a fight for life or death.moreless
Jordan and Peter travel outside the safety of the abbey to retrieve some specimens and discover just what's living in the woods. At the same time, Sister Amy plots to make the CDC team leave forever.moreless
The victim: John Rivera; the killer: Isabelle Flores
John, the the chairman of the Green Point Equestrian Centre, is found trampled to death in the stables. The death may have been ruled accidental but, in her autopsy, Betty found huge quantities of the animal tranquilizer ketamine in his system. Had the horse not trampled John, the ketamine would have killed him. Isabelle is the nanny to Becky Hill, who, with her mother Victoria, are the newest members of Green Point.
George finds himself caring for Tansy's prized dog, and he panics when the dog goes missing. Wade starts to become upset by his lack of time alone with Zoe, especially as she focuses on not losing her good standing in BlueBell to a new doctor, named Jonah, who is also Brick's nephew. Brick is ready to reveal his relationship with Shelby to the resident of BlueBell, but Lemon and Magnolia are trying everything to get rid of her. Meanwhile, Lavon has to clear the air with someone before he embarks on a new relationship.moreless
Zoe blames herself when one of her friends struggles with a health problem and Zoe didn't notice the symptoms. Lavon encourages Wade to follow his dream of opening his own bar in Bluebell. Lemon, hoping to repair her relationship with George, plans a romantic night for two of them.moreless
Levon notices that Zoe is feeling homesick and asks her to host his annual pre-game homecoming party to help her feel more connected to Bluebell. Zoe gladly accepts his offer and asks her New York friend Gigi for help. Zoe learns, however, that New York and Bluebell have very different ideas of what makes a good party. Meanwhile, George and Wade devise a plan to get revenge on their high school nemesis, Jimmy. When when Lemon learns of their scheme, she wants in on the action, too.moreless
Don may find his past casesscrutinized as Abby and Lina investigate his former partner Paul, for the attempted murder of his wife. Meanwhile, Lina is worried about the working relationship she and Abby have but is wondering if the relationship will change due to the upcoming birth of her baby. Abby's relationship with Danny and Brody begins to heat up as both continue to compete for her.moreless
Fiona and Jesse work together for a pharmaceuticals magnate, but soon realize that he is hiding something. Meanwhile, Michael and Sam take on a bomb-maker involved in Max's death.
Josh struggles to keep an equilibrium between his human self and his supernatural self, and Sally has am epiphany regarding her situation. Aidan befriends a neighbour's boy.
Josh and Emily go to their parents house at the behest of Aidan after Emily gets hurt by Marcus. Aidan follows him and tries to help his parents understand their son but the past catches up to them both when Marcus comes to the house against Bishop's orders and fights it out with Aidan. Meanwhile, Sally tries to convince Bridget that Danny killed her. But Danny still manipulative as ever convinces Bridget it was just an accident.moreless
Michael teams up with Vaughn in order to bring down John Barrett, the man behind the Bible book code.
Meanwhile, defense attorney Adam Scott asks for Michael's help, after his daughter has been kidnapped.