As Holmes and Watson work a standard murder investigation, they encounter MI-6 and find the case has international and political inferences. Watson re-examines her relationships with Mycroft and Sherlock.
Holmes and Watson chase the source of a lethal toxin after a pickpocket dies of anthrax poisoning.
Holmes and Watson investigate when a presumed dead serial killer looks as if he's killing again.
Holmes and Watson investigate when an influential cancer researcher is murdered. They must figure out if his new cutting-edge invention played any part in his death. Detective Bell is given clearance to resume field work.moreless
Holmes and Watson are called in to consult when a woman, who was thought murdered by her husband years ago, appears now to be a victim of a kidnapping after her husband receives a ransom demand. Holmes and Watson are eager for Lestrade to leave the brownstone but he doesn't seem inclined to do so.moreless
Tensions rise when Sherlock and Watson are teamed up with Lestrade to find the person responsible for a bombing.
When a up-and-coming ballerina is murdered, Sherlock is called in to solve the case. Watson tries to find a homeless veteran after his friend reports him as kidnapped.
As Watson peruses one of Holme's cold cases, she figures out that a rare prehistoric fossil is tied to the unsolved murder. Sherlock is in uncharted territories as concerns his duties as a sobriety sponsor.moreless
While Holmes tries to make amends with Detective Bell, he and Watson look into the mafia's association with a body found in a barrel.
Moriarty is brought in to consult on a kidnapping case, bringing Holmes and Watson face to face with their former adversary. Detective Bell persists in his efforts to make a full recovery.
Holmes and Watson set out to determine which client killed a hedge fund manager running a Ponzi scheme. Sherlock considers becoming a sponsor for a recovering addict.
An official police inquiry into one of Sherlock's investigations puts his and Watson's future with the NYPD on the line.
It's the NYPD versus Holmes and Watson when the two sleuths uncover a cold case serial killer.
Mycroft shows up in New York to ask Holmes and Watson to solve a case concerning his former fiancée. Mycroft and Joan's relationship is a source of contention with Sherlock.
As Holmes and Watson investigate the murder of a financial consulting company's CEO, a mysterious woman from Holmes' past surfaces as a suspect.
Watson and Holmes search for the civil contractor responsible for leaking classified information but soon find themselves targeted by cyber activists. Joan decides to sign up at an online dating service.
Holmes and Watson investigate the murder of a well-respected mathematician and look into the guarded equation he was trying to decipher. Watson is at a loss when a former patient's son asks her for a loan.moreless
Holmes and Watson head to London for an unsolved mystery investigation and to look up his former mentor, Gareth Lestrade. Sherlock joins up with his estranged brother, Mycroft, who discloses some secrets.
A drug deal gone bad results in two deaths and a wounded accomplice. When Danny gets to the hospital Linda won't allow him to question the suspect until after surgery. A battle ensues between Danny and Linda when the suspect dies in surgery.moreless
While trying to predict the next move of erratic criminal Martin Ennis, Sherlock is forced to work with an FBI profiler. The same profiler who wrote an acclaimed book about the notorious criminal. Elsewhere, Watson faces eviction from her apartment.moreless
A British criminal with strong ties to Sherlock's past has shown up in New York. Watson isn't sure about whether to take on a new client.
A stabbing death has Danny investigating a voodoo community. Garrett discusses a dark secret with Frank. Jack and Sean head out with Erin and Nicky for some trick or treating.
When two separate murder victims are found to be part of a group charged with gang rape, Danny considers the possibility that the same person killed them both. Erin faces off in court against her ex-husband Jack Boyle.moreless
After family is robbed and beaten and the assailant is shot and killed, the Reagans discuss how far they'd go to protect their family. Frank is conflicted with charges brought against a girl arrested at a rally when her identity is revealed.moreless