Jon Stewart knew how to address comedy in a political sphere rather easily. More importantly, he understood how to make the show fun, interesting, and those around him want to come to work and vice versa. He is a social comedic genius that understood that people needed to be stood up for while others needed to be chastized.
One thing I never realized though until I started researching was that Daily Show Jon Stewart was a chemistry major in college before he changed over into psychology for some time.