When evidence surfaces in form of several pictures at a crime scene on the Brooklyn Bridge, the CSIs rush to San Francisco to search for a 16-year-old girl who might be dead already. The case hits home for Jo.
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Officer Jessica Tang is served with divorce papers in the morning that appears to have affected her judgment in a shooting later in the shift. Sammy Bryant holds a grudge against Ben Sherman for not backing him up over drug evidence that may have been planted during a previous arrest. Meanwhile, Lydia is still hesitant to discuss her pregnancy with Ruben and Det. Fernandez.
Grace has trouble dealing with a food issue and doesn't go to anybody for help to deal with it. Neely's having trouble moving when her drug problem spirals out of control. A friend of Butch's needs help getting out of a tough situation.
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The final challenge between Dexter and Arthur comes. Debra finds out a long hidden truth. Rita admits that her marriage is troubled. Batista's and LaGuerta's relationship must face consequences.