Karen's single You Don't Know Love from her album The Third Time reached the Top 30 in the charts.
Karen performed the song I Am Australian at the Prime Minister's Dinner during Melbourne's Olympic Bid.
Karen's seventh album, On A Clear Day, was released in 2003, and features 11 songs including When I Grow Too Old To Dream and The Rose.
Karen's partner on It Takes Two is Richard Zachariah.
Karen appeared in the show Burke's Backyard with Don Burke as a celebrity gardener.
Karen recorded her fifth album, Moonglow in the United States.
In 1990, Karen joined The Seekers, which is a group of Australian folk-influenced musicians, and which was formed in 1962 in Melbourne.
Karen has performed in numerous Christmas concerts, such as the Carols by Candlelight in Melbourne, and the Carols in the Domain in Sydney.
Karen was appointed as the National Patron for the Australian Girls Choir in 1989.
Karen was nominated for Best New Talent in the TV Week/Countdown Rock Awards in 1992.
Karen has performed in various national and international events such as the Australian Olympic Committee Dinner, Tokyo's Australian Society Ball, and the ABM Top 500 Business People of the Year Awards.
In 1998, the Reconciliation Council appointed Karen as one of its Inaugural Ambassadors for Reconciliation.
Karen opened up her own school called the Karen Knowles Singing School in 2004.
In 1999, Karen recorded her sixth album, entitled By Request, which featured her most requested songs.
In 1998, Karen was nominated for an Australian Humanitarian Award for her services to the arts.
Karen recorded her fourth album, A Night of Carols in 1991, which featured the Australian Girls Choir.
After moving to London in 1984, Karen returned to Australia in 1988, and was featured in the musical, Big River as Mary Jane Wilks.
In 1982, her first album You Are The Reason achieved the Platinum status.
In 1981, Karen received a Gold record for her single Why Won't You Explain.
In 1980, Karen was signed to the Fable label of Ron Tudor.
Karen first became famous by joining the talent show Young Talent Time in 1975.
Karen: (On Young Talent Time) It was such a part of people's lives. I didn't have a concept of that because I was in it, but for everybody else then, the football and Young Talent Time were a major part of the Australian way of life.
Karen: I'm just passing on what I've learnt over my career, which started when I was very young. Obviously, I'll finetune his vocal technicalities and focus on choosing the right song that suits us both..
- on what he expects of his partner he'll be working with on his new show, 'It Takes Two' .