Sam goes to check out a report of peaceful people transforming into violent killers and discovers a connection to a case involving his grandfather. Meanwhile, Dean deals with the aftermaths of acquiring the Mark of Cain and Crowley is eager to take advantage of his weakness.moreless
Kate is ordered by Judge Nicastro to mediate an insurance dispute.
The translucent shapeshifters return to plague Fringe division, and a former Massive Dynamic scientist is involved. Meanwhile, Walter meets with Nina Sharp.
Jaime continues to gradually adjust to her new bionic life - all while trying to maintain the normal aspects of her human life. She also befriends a stranger who knows more about her than she thinks, and later goes on her first mission.moreless
Apollo assists in the search for a missing Raptor team as the new commander of the Pegasus grows increasingly unstable.