Dean is devastated by the fact that the doctor tells him Sam won't make it, so he promises any angel willing to help that he will owe them a favor. Many angry angels want to find Dean and kill him, but Ezekiel gets to him first. At the same time, Sam is fighting for his life, and Castiel has a hard time surviving without his powers.moreless
A female car accident victim is brought to the ER, and the staff immediately blames her boyfriend for causing the accident, which stirs some painful memories for Will. Emily learns that her patient is refusing to undergo surgery to treat her cancer, fearing that reconstructive surgery will damage both her career and her relationship. Meanwhile, as Will prepares for an upcoming exam, he struggles to decide between using Cassandra's study method over Emily's legendary flashcards, which brings out Emily's competitive side.moreless
Emma and Regina share a common suspicion over a newcomer to Storybrooke, while David and Mary Margaret try to cope with their feelings. Meanwhile, in the fairytale world, Prince Charming's wedding with King Midas' daughter approaches while Snow tries to cope with her feelings.moreless
Magnus and Henry attempt to infiltrate a secret Abnormal testing facility run by Homeland Security and encounter an old friend whose loyalties are once again in question - Nikola Tesla.
With all others in the line of succession dead, Laura Roslin, the Secretary of Education, is appointed President of the Twelve Colonies. She plans to gather up all the ships that survived the Cylon attack, including the Galactica, and flee the Colonial homeworlds, never to return.moreless
Over forty years have passed since the end of the Cylon War, contested between the humans of the Twelve Colonies and man's creation, the Cylons.
The Galactica, one of the original twelve battlestars, is scheduled to be decommissioned. As part of the ceremonies, Commander Adama's son Lee ("Apollo") is named to fly Adama's restored Viper. Lee's return opens old wounds when they discuss the fate of Adama's other son, Zak.
Meanwhile, in Caprica City, the famous scientist Gaius Baltar argues against limits on research into artificial intelligence. He also has a sensual new lover with a mysterious agenda of her own.