Spider-Man, Iron Man, Thor and Hulk stand powerless after being struck by Dr. Doofenshmirtz's power-draining "inator." Once the Marvel Super Villains - Red Skull, Whiplash, Venom and M.O.D.O.K. - find out that Dr. Doofenshmirtz is responsible for robbing the superheroes of their powers, they seek him out and together create mayhem in Danville. Meanwhile, Phineas and Ferb do everything they can to restore the superheros' powers before the evil villains take over the world.moreless
The Avengers face a superior technological, power-replicating machine that can turn the Avengers abilities against them and only Captain America's dependency on non-technology can save the day.
When Dr. Doom sends an Asgardian weapon equiped Midgard Serpent to destroy the earth, Thor decides to sacrifice himself.
After having been disbanded for years, the Avengers reunite when Red Skull, having formed an unlikely alliance with M.O.D.O.K., kills Captain America, and the heroes must avenge their fallen comrade and foil whatever plan the Skull is concocting.moreless
M.O.D.O.K. uses his technology to mind control the Avengers, causing them to brutally attack each other, as Red Skull infiltrates the Mansion to carry out a devious plot that puts the entire city of Manhattan at risk.moreless